Senior Bioanalytical Scientist - Remote

Placements24; Vereeniging; Hybrid; ZAR 900,000 - 1,500,000; Full time

Benefits offered by this job

Remote work

Home office stipend

Health coverage

Retirement savings plan

Paid time off

Professional development support

Job summary

Placements24 is seeking a Senior Bioanalytical Scientist to join a fully remote, global pharmaceutical research team. The role focuses on developing and validating advanced bioanalytical methods, including LC-MS/MS and immunoassays, to support drug development programs.

You will work independently in a virtual environment, manage multiple projects, mentor junior scientists, and contribute to regulatory submissions while staying current with GLP/GCP/ICH guidelines and data integrity standards.

Qualifications

• Ph.D. in Analytical Chemistry, Biochemistry, Pharmacology or related field.
• 5–7 years hands-on bioanalytical method development and validation in pharma/CRO.
• Expertise in LC-MS/MS and immunoassays (ELISA, ECL, RIA) and GLP/GCP/ICH know-how.
• Experience with various biological matrices and regulatory reporting.

Responsibilities

• Develop, validate, and implement bioanalytical assays (LC-MS/MS, ELISA) for drugs and biomarkers.
• Analyze samples for preclinical/clinical studies and ensure data integrity.
• Troubleshoot assays and optimize workflows.
• Prepare validation reports and contribute to regulatory submissions.
• Mentor junior scientists and collaborate with cross-functional teams.
• Manage multiple projects remotely with strong time management.

Skills

LC-MS/MS

Immunoassays

Bioanalytical

Data analysis

Regulatory knowledge

Project management

Mentoring

Remote work

Education

Ph.D. in Analytical Chemistry

Tools

Sciex Analyst

MassHunter

Waters Empower

Thermo Fisher Analyst

Job description

About the Role

Our client, a pioneering pharmaceutical research organization, is actively seeking a highly skilled Senior Bioanalytical Scientist to join their fully remote, global research team. This position is essential for developing and validating advanced bioanalytical methods to support drug development programs. You will leverage your expertise in LC-MS/MS, immunoassays, and other cutting‑edge techniques to quantify drug concentrations and biomarkers in various biological matrices. This remote‑first role requires a proactive, self‑motivated individual who thrives in a collaborative virtual environment and can independently manage complex analytical projects. You will play a critical role in generating robust data that underpins critical decision‑making throughout the drug development lifecycle, contributing significantly to the advancement of novel therapeutics. The role is ideal for an experienced scientist looking for an impactful career opportunity with unparalleled flexibility.

Key Responsibilities

• Develop, validate, and implement sensitive and specific bioanalytical assays (e.g., LC-MS/MS, ELISA, MSD) for small molecules, biologics, and biomarkers in biological matrices (plasma, serum, urine, tissue).
• Perform routine sample analysis for preclinical and clinical studies, ensuring data integrity and timely reporting.
• Troubleshoot assay performance issues, optimize methodologies, and implement improvements.
• Maintain laboratory equipment, ensuring calibration and adherence to maintenance schedules.
• Ensure all bioanalytical activities are conducted in compliance with regulatory guidelines (e.g., FDA, EMA, ICH).
• Prepare method validation reports, study reports, and contribute to regulatory submission documents.
• Stay current with scientific literature, new technologies, and industry best practices in bioanalysis.
• Collaborate effectively with cross‑functional teams, including discovery, DMPK, and clinical development groups.
• Mentor junior scientists and provide technical guidance on bioanalytical methodologies.
• Manage multiple projects simultaneously, ensuring adherence to timelines and quality standards in a remote setting.

Requirements

• Ph.D. in Analytical Chemistry, Biochemistry, Pharmacology, or a related field.
• A minimum of 5-7 years of hands‑on experience in bioanalytical method development and validation in a pharmaceutical or contract research organization (CRO) setting.
• Expertise in LC-MS/MS instrumentation and data analysis software (e.g., Sciex, Waters, Thermo Fisher, Analyst, SciexOS, MassHunter).
• Strong experience with immunoassay techniques (e.g., ELISA, ECL, RIA) is a significant advantage.
• Proficiency in handling various biological matrices and understanding their implications for assay performance.
• Thorough knowledge of regulatory guidelines (GLP, GCP, ICH) pertaining to bioanalysis.
• Excellent data analysis, interpretation, and report‑writing skills.
• Strong organizational and time management skills to manage multiple concurrent projects effectively in a remote environment.
• Exceptional problem‑solving abilities and a proactive approach to challenges.
• Demonstrated ability to work independently and collaboratively within a virtual team.

Benefits

This fully remote position offers a competitive annual salary of ZAR, along with a comprehensive benefits package including excellent health coverage, retirement savings plan, and generous paid time off. We provide a stipend for home office setup and ongoing support for professional development, including attendance at scientific conferences. Our client is dedicated to fostering a productive and engaging remote work culture where scientific excellence is paramount.