Senior Analytical Chemist - Pharmaceutical R&D

Placements24; Bloemfontein; Hybrid; ZAR 700,000 - 1,000,000; Full time

Job summary

Placements24 in Bloemfontein is seeking a Senior Analytical Chemist to develop, validate, and implement analytical methods for drug substances and products. You will use HPLC, GC, MS and spectroscopy to ensure quality and regulatory readiness.

The role requires a MSc/PhD in Chemistry with 5+ years in pharmaceutical analytical chemistry, strong ICH/GMP knowledge, and hands-on instrument expertise. Hybrid work and ongoing training are available.

Qualifications

• Requires MSc or PhD in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or related field.
• Minimum 5 years of pharmaceutical analytical chemistry experience with strong ICH and GMP knowledge.
• Hands-on experience with chromatographic and spectroscopic techniques.
• Proficiency in data analysis software and instrument software packages.
• Strong problem-solving and meticulous attention to detail, based in Bloemfontein.

Responsibilities

• Develop, optimize, and validate analytical methods for drug substances and products using HPLC, GC, MS, and spectroscopy.
• Perform routine and non-routine analytical testing to support formulation development, stability studies, and QC.
• Operate and maintain analytical instruments with proper calibration and performance checks.
• Troubleshoot analytical methods and instrumentation issues and provide timely solutions.
• Contribute to analytical sections for regulatory filings (e.g., CTD modules).

Skills

Analytical chemistry

Regulatory compliance

Troubleshooting

Attention to detail

Education

MSc or PhD in Chemistry/Analytical Chemistry/Pharmaceutical Sciences

Tools

HPLC

GC

MS

Spectroscopy

Job description

Key Responsibilities

• Develop, optimize, and validate analytical methods for the characterization of drug substances and products using techniques like HPLC, GC, MS, and spectroscopy.


• Perform routine and non-routine analytical testing to support formulation development, stability studies, and quality control.


• Operate and maintain a range of analytical instruments, ensuring proper calibration and performance.


• Troubleshoot analytical methods and instrumentation issues, providing timely solutions.


• Contribute to the preparation of analytical sections for regulatory filings (e.g., CTD modules).

Requirements

• M.Sc. or Ph.D. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related discipline.


• Minimum of 5 years of experience in pharmaceutical analytical chemistry, with a strong understanding of ICH guidelines and GMP principles.


• Extensive hands-on experience with various chromatographic and spectroscopic techniques.


• Proficiency in data analysis software and instrument software packages.


• Strong problem-solving abilities and attention to detail, essential for working in Bloemfontein .

Benefits

• Competitive annual salary and bonus structure.


• Comprehensive medical and retirement benefits.


• Opportunities for advanced training and professional growth.


• Access to state-of-the-art analytical instrumentation and a supportive R&D environment.


• Hybrid work arrangement offering a balance between lab work and flexible office time.

Our client is seeking a highly skilled Senior Analytical Chemist to join their pharmaceutical research and development division in Bloemfontein . This role is crucial for ensuring the quality, safety, and efficacy of new drug formulations through rigorous chemical analysis. You will be responsible for developing, validating, and implementing analytical methods, troubleshooting instrumentation, and contributing to regulatory submissions. This is an excellent opportunity to work with advanced analytical technologies in a collaborative R&D setting and make a significant impact on drug development.