Research Chemist: Complex Organic Synthesis Drug Discovery

Placements24; Centurion; Hybrid; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Competitive salary

Conferences

Advanced facilities

Flexible work arrangements

Job summary

Placements24 seeks a highly skilled Research Chemist specialized in Organic Synthesis to join our R&D team in Centurion. You will design and execute complex synthetic routes to API-level targets, optimize conditions for yield and scalability, and collaborate with medicinal chemists to drive drug discovery in a state-of-the-art lab.

The ideal candidate holds a Ph.D. in Organic Chemistry with at least 4 years of post-doctoral or industrial experience, strong mechanistic knowledge, and proficiency

Qualifications

• Ph.D. in Organic Chemistry required.
• Minimum of 4 years post-doctoral or industrial experience in synthetic organic chemistry.
• Proven track record in designing and executing complex total syntheses of natural products or pharmaceuticals.

Responsibilities

• Design and execute multi-step synthetic routes for complex organic molecules, intermediates, and APIs.
• Optimize reaction conditions to improve yield, purity, and scalability of synthetic processes.
• Utilize a wide range of modern synthetic organic chemistry techniques and instrumentation.
• Characterize synthesized compounds using spectroscopic methods (NMR, MS, IR) and chromatographic techniques (HPLC, GC).
• Collaborate closely with medicinal, process, and analytical chemists to advance drug discovery projects.
• Troubleshoot synthetic challenges and identify solutions to overcome obstacles.

Skills

Organic synthesis

Retrosynthetic analysis

Spectroscopy

Chromatography

Problem solving

Education

Ph.D. in Organic Chemistry

Tools

NMR

Mass spectrometry

IR

HPLC

GC

Job description

Placements24 seeks a highly skilled Research Chemist specialized in Organic Synthesis to join our R&D team in Centurion. You will design and execute complex synthetic routes to API-level targets, optimize conditions for yield and scalability, and collaborate with medicinal chemists to drive drug discovery in a state-of-the-art lab.

The ideal candidate holds a Ph.D. in Organic Chemistry with at least 4 years of post-doctoral or industrial experience, strong mechanistic knowledge, and proficiency