Remote Principal Statistical Programmer — SAS, R Expert

Watchmaker Genomics, Inc.; Cape Town; Remote; ZAR 1,488,000 - 2,810,000; Full time

Job summary

Cytel Inc. is seeking a Senior/Principal Statistical Programmer (SAS + R) to work remotely within our sponsor-dedicated model. The role involves leading programming for clinical development programs, overseeing CROs, and delivering high-quality SDTM/ADaM outputs in alignment with FDA regulations.

The ideal candidate has 7+ years of experience in biostatistics programming, strong SAS skills, CDISC expertise, and the ability to work independently with minimal supervision.

Qualifications

• Minimum bachelor's degree in computer science, data science, mathematics, or statistics.
• 7+ years of experience as a Statistical Programmer on a Biotech/Pharma Biostatistics or similar team.
• Exceptional SAS programming skills and expertise in statistical programming procedures in a clinical development environment.
• Extensive experience with CDISC standards (SDTM, ADaM, Define.xml).
• Experience supporting regulatory submissions and interacting with FDA or global authorities.
• Ability to work independently and lead project efforts; strong written and verbal communication.

Responsibilities

• Generate SDTM, ADaM specifications, datasets, reviewer’s guides and define.xml files for multiple studies.
• Develop SAS programs to create datasets, listings, tables, and graphs.
• Deliver high-quality SAS/R outputs for clinical programs and oversee CRO programmers.
• Support preparation of clinical study reports, regulatory submissions, publications, and DSURs.
• Contribute to standards for programming tools, outputs, and macros.
• Develop CRFs, edit checks, and data validation plans; review external vendor data.

Skills

Leadership

Communication

Independent working

SAS programming

CDISC standards

Education

Bachelor's degree in computer science, data science, mathematics, or statistics

Tools

SAS

R

Python

Java

Shiny

Unix/Linux

git

Job description

Cytel Inc. is seeking a Senior/Principal Statistical Programmer (SAS + R) to work remotely within our sponsor-dedicated model. The role involves leading programming for clinical development programs, overseeing CROs, and delivering high-quality SDTM/ADaM outputs in alignment with FDA regulations.

The ideal candidate has 7+ years of experience in biostatistics programming, strong SAS skills, CDISC expertise, and the ability to work independently with minimal supervision.