Principal Scientist - Process Development

Placements24; Vereeniging; Ibrido; ZAR 1.200.000 - 1.900.000; Tempo pieno

Vantaggi offerti da questo lavoro

Excellent compensation and bonus

Health, dental, and vision benefits

Home office equipment allowance

Flexible remote work

Descrizione del lavoro

Placements24 is seeking a Principal Scientist to lead Process Development in a fully remote capacity. You will optimize and scale up chemical manufacturing processes for novel compounds, leveraging extensive chemical engineering and process chemistry expertise to design, validate robust manufacturing protocols.

The role emphasizes remote leadership, collaboration with a global team, and oversight of pilot-scale studies, process control, and regulatory compliance (GMP).

Competenze

• PhD in Chemical Engineering, Chemistry, or a related field.
• Minimum of 10 years of experience in process development and scale-up within pharma or fine chemicals.
• Deep understanding of reaction kinetics, thermodynamics, and mass transfer principles.
• Proven experience designing and implementing GMP-compliant processes.
• Expertise in PAT and SPC forprocess control and quality.
• Strong leadership, project management, and remote collaboration skills.

Mansioni

• Lead development and optimization of scalable chemical processes for manufacturing APIs and intermediates.
• Design and execute pilot-scale studies to assess process feasibility and identify parameters.
• Develop robust process control strategies and ensure GMP compliance.
• Troubleshoot complex process issues to improve yield, purity, and efficiency.
• Collaborate remotely with research chemists, analytical scientists, and manufacturing teams.
• Mentor junior scientists and engineers, fostering continuous improvement and innovation.

Conoscenze

Leadership

Project management

Remote collaboration

Mentoring

Process development

GMP compliance

Formazione

PhD in Chemical Engineering, Chemistry, or related

Strumenti

PAT

SPC

Descrizione del lavoro

About the Role

Our client is seeking a highly accomplished Principal Scientist to lead their Process Development efforts in a fully remote capacity. This senior role is crucial for optimizing and scaling up chemical manufacturing processes for novel compounds. You will leverage your extensive expertise in chemical engineering and process chemistry to design, implement, and validate robust and efficient manufacturing protocols. This position offers the unique opportunity to drive critical innovation in process development from your remote location, working closely with a talented, distributed global team. Ideal for a seasoned expert looking for a challenging remote leadership opportunity.

Key Responsibilities

• Lead the development and optimization of scalable chemical processes for manufacturing APIs and intermediates.
• Design and execute pilot-scale studies to assess process feasibility and identify critical parameters.
• Develop robust process control strategies and ensure compliance with regulatory requirements (e.g., GMP).
• Troubleshoot complex process issues and implement effective solutions to improve yield, purity, and efficiency.
• Collaborate closely with research chemists, analytical scientists, and manufacturing teams virtually.
• Mentor junior scientists and engineers, fostering a culture of continuous improvement and innovation.

Requirements

• Ph.D. in Chemical Engineering, Chemistry, or a related field.
• Minimum of 10 years of experience in process development and scale-up within the pharmaceutical or fine chemical industry.
• Deep understanding of reaction kinetics, thermodynamics, and mass transfer principles.
• Proven experience in designing and implementing GMP-compliant processes.
• Expertise in process analytical technology (PAT) and statistical process control (SPC).
• Strong leadership, project management, and remote collaboration skills.

Benefits

• Exceptional salary and bonus structure commensurate with experience.
• Comprehensive health, dental, and vision benefits.
• Generous allowance for professional development, training, and home office equipment.
• Flexible remote working arrangements.
• Opportunity to significantly impact the manufacturing of critical chemical products.