Remote Senior Chemical Process Engineer - Pharmaceutical Intermediates

Placements24; Mbombela (Nelspruit); Híbrido; ZAR 900.000 - 1.300.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Health coverage

Retirement plans

Performance-based bonuses

Online training

Career advancement

Remote work

Descripción de la vacante

Placements24 is seeking a Senior Chemical Process Engineer to join our client’s fast-growing pharmaceutical manufacturing team on a fully remote basis. This role focuses on design, optimization, and scale-up of processes for APIs and intermediates, ensuring cGMP compliance and high quality.

You will use Aspen Plus or similar tools, lead scale-up activities, perform PHAs and risk assessments, and collaborate across R&D, QA, Manufacturing worldwide.

Formación

• Bachelor’s or Master’s degree in Chemical Engineering or related field.
• Minimum 8 years in chemical process engineering, pharma focus.
• Strong knowledge of cGMP and regulatory guidelines.
• Experience with Aspen Plus or HYSYS and P&ID development.

Responsabilidades

• Design and optimize processes for APIs and intermediates.
• Lead scale-up from lab to commercial manufacturing.
• Perform process hazard analyses and risk assessments.
• Collaborate with R&D, QA, Manufacturing across geographies.
• Provide mentorship to junior engineers.

Conocimientos

Process engineering

Pharma manufacturing

Remote collaboration

Project management

cGMP knowledge

Educación

Bachelor's or Master's in Chemical Engineering

Herramientas

Aspen Plus

HYSYS

P&ID

Statistical analysis

Descripción del empleo

About the Role

Our client, a fast-growing pharmaceutical manufacturing company, is seeking a highly experienced Senior Chemical Process Engineer to join their innovative team on a fully remote basis. This role is crucial for the design, optimization, and scale-up of complex chemical processes used in the production of active pharmaceutical ingredients (APIs) and intermediates. You will be responsible for ensuring that all processes meet rigorous quality, safety, and regulatory standards (cGMP). Leveraging advanced simulation tools and your extensive engineering expertise, you will troubleshoot existing processes, develop new manufacturing routes, and contribute to the continuous improvement of production efficiency. This is an exceptional opportunity for a motivated engineer to make a significant impact from the comfort of their home office, working with a globally recognized leader in the pharmaceutical sector.

Key Responsibilities

• Design, develop, and optimize chemical processes for the synthesis of pharmaceutical intermediates and APIs, ensuring cGMP compliance.
• Conduct process simulations and modeling using software such as Aspen Plus or similar, performing mass/energy balance calculations and P&ID development.
• Lead scale-up activities from laboratory and pilot plant to commercial manufacturing, managing associated risks and challenges.
• Troubleshoot and resolve process-related issues encountered in manufacturing, identifying root causes and implementing effective solutions.
• Perform thorough process hazard analyses (PHAs) and implement robust safety measures in line with industry best practices.
• Evaluate new technologies and equipment to improve process efficiency, yield, and product quality.
• Prepare detailed process documentation, including batch records, validation protocols, and technical reports.
• Collaborate effectively with R&D, Quality Assurance, Manufacturing, and Project Management teams across different geographies.
• Provide technical support and mentorship to junior engineers and operators.

Requirements

• Bachelor's or Master's degree in Chemical Engineering or a related discipline.
• A minimum of 8 years of experience in chemical process engineering, with a strong focus on pharmaceutical manufacturing or fine chemicals.
• In-depth knowledge of cGMP regulations and guidelines applicable to pharmaceutical production.
• Proficiency in process simulation software (e.g., Aspen Plus, HYSYS) and statistical analysis tools.
• Experience with process safety evaluations (e.g., HAZOP) and risk management.
• Strong understanding of organic chemistry principles as they apply to process scale-up.
• Demonstrated ability to manage complex projects and drive continuous improvement initiatives.
• Excellent analytical and problem-solving skills, with meticulous attention to detail.
• Superior communication and interpersonal skills, essential for effective remote collaboration.
• Proven ability to work independently and manage time effectively in a remote work environment.

Benefits

• This **remote** position offers a competitive salary and a comprehensive benefits package, including excellent health coverage, retirement savings plans, and performance-based bonuses.
• Our client is committed to professional development, providing access to online training, virtual conferences, and opportunities for career advancement.
• Enjoy the flexibility and work-life balance that comes with a **remote** role, while making a critical contribution to the development of life-saving medicines for Our client.