Principal Research Scientist (Biotechnology)

Placements24; Polokwane; Hybrid; ZAR 1,200,000 - 2,100,000; Full time

Benefits offered by this job

Competitive salary

Annual bonus

Stock options

Professional development

Hybrid work model

Relocation support

Job summary

Placements24 seeks a Principal Research Scientist to lead high-impact biotherapeutics research in Polokwane, Limpopo. You will design strategies, oversee labs, and mentor scientists to drive drug discovery.

The role requires a PhD with 7+ years post-doctoral leadership, expertise in molecular/cell biology and drug discovery processes, and a track record of successful projects in industry or academia.

Qualifications

• PhD in Molecular Biology, Cell Biology, Biochemistry, Pharmacology or related life sciences.
• Minimum 7 years post-doctoral experience with leadership.
• Proven track record managing research projects from conception to completion.
• Experience in protein engineering, antibody development, gene therapy or immunology.

Responsibilities

• Lead independent research projects on discovery and development of novel biotherapeutics.
• Design and execute complex molecular and cell biology experiments.
• Analyze data, formulate hypotheses and guide follow-up investigations.
• Mentor and supervise research staff and associates.
• Collaborate with cross-functional teams (chemistry, pharmacology, regulatory).
• Present findings at conferences and contribute to patents and reports.
• Ensure rigorous documentation and reproducibility of experiments.
• Contribute to strategic direction of R&D and identify new opportunities.

Skills

Molecular biology

Cell biology

Biochemistry

Pharmacology

Leadership

Mentorship

Data interpretation

Scientific communication

Education

PhD in life sciences

Tools

ELISA

Western blot

Flow cytometry

Cell-based assays

Job description

About the Role

Our client, a cutting-edge biotechnology firm at the forefront of developing novel biopharmaceuticals, is seeking a highly accomplished Principal Research Scientist to join their R&D division in Polokwane, Limpopo . This pivotal role involves leading complex research projects aimed at discovering and developing new therapeutic agents. You will be responsible for designing experimental strategies, overseeing laboratory work, interpreting data, and contributing significantly to the company's drug discovery pipeline. The ideal candidate will possess a deep understanding of molecular biology, cell biology, and drug discovery principles, along with strong leadership and mentorship skills. This is an exceptional opportunity to make a significant impact on human health and advance your career within a dynamic and innovative scientific community. Join us in Polokwane and contribute to the future of medicine.

Key Responsibilities

• Lead independent research projects focused on the discovery and development of novel biotherapeutics.
• Design and execute complex experimental protocols involving molecular and cell biology techniques.
• Analyze and interpret experimental data, drawing conclusions and formulating hypotheses for further investigation.
• Oversee and mentor a team of research associates and scientists, providing scientific guidance and technical expertise.
• Collaborate with cross-functional teams, including chemistry, pharmacology, and regulatory affairs, to advance projects.
• Stay abreast of the latest scientific literature and technological advancements in biotechnology and drug discovery.
• Prepare research reports, contribute to patent applications, and present findings at scientific conferences.
• Ensure the highest standards of experimental rigor, reproducibility, and documentation.
• Contribute to the strategic direction of the R&D department and identify new research opportunities.

Requirements

• Ph.D. in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related life sciences field.
• Minimum of 7 years of post-doctoral research experience in an industrial or academic research setting, with demonstrated leadership.
• Proven track record of successfully managing research projects from conception to completion.
• Extensive experience in one or more of the following areas: protein engineering, antibody development, gene therapy, or immunology.
• Proficiency in a wide range of molecular and cell-based assays (e.g., ELISA, Western Blotting, flow cytometry, cell-based assays).
• Strong understanding of drug discovery processes and regulatory pathways.
• Excellent analytical, problem-solving, and critical thinking skills.
• Superb written and oral communication skills, with the ability to present complex scientific information effectively.
• Experience working in a hybrid research environment.
• Must be legally authorized to work in South Africa and based in or willing to relocate to Polokwane .

Benefits

• A highly competitive annual salary package of R. Comprehensive medical, dental, and vision insurance coverage.
• Generous annual bonus based on individual and company performance.
• Stock options or equity grants available.
• Support for professional development, including conference attendance and advanced training.
• Flexible working arrangements, accommodating a hybrid work model.
• Opportunity to work on transformative therapies in Polokwane .
• Collaborative and scientifically stimulating work environment.