Lead Systems Biologist

Placements24; Stellenbosch; On-site; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Health insurance

Dental coverage

Vision coverage

Retirement plan

Professional development

Conference participation

Job summary

Placements24 is seeking a Lead Systems Biologist to join its renowned research facility in Stellenbosch, Western Cape. The role focuses on integrating multi-omics data, building computational models, and validating predictions in an advanced research setting.

The successful candidate will lead a team of systems biologists and bioinformaticians, drive innovative projects, and contribute to strategic development of the systems biology program. A PhD with extensive modeling experience is required.

Qualifications

• PhD in Systems Biology or related quantitative field.
• Strong background in computational modeling of biological systems.
• Experience with multi-omics data integration.

Responsibilities

• Lead development and application of computational models for complex biological systems.
• Integrate genomics, transcriptomics, proteomics, and metabolomics data into system models.
• Oversee experimental validation studies to test model predictions.
• Mentor a team of systems biologists and bioinformaticians.
• Collaborate across disciplines to address key biological questions.
• Develop and implement novel computational methods for systems-level analysis.
• Disseminate findings via high-impact publications and talks.
• Contribute to grant proposals and secure funding.
• Ensure robust data management and reproducible research practices.

Job description

About the Role

Our client, a renowned research institution focused on understanding complex biological systems, is seeking an experienced Lead Systems Biologist to join their advanced research facility in Stellenbosch, Western Cape . This leadership position is crucial for integrating multi-omics data, computational modeling, and experimental validation to elucidate cellular mechanisms and disease pathways. You will lead a team of talented scientists, drive innovative research projects, and contribute to the strategic development of the systems biology program. The ideal candidate will have a strong quantitative background, extensive experience in computational modeling of biological systems, and a passion for unraveling biological complexity. This role offers a unique opportunity to make significant contributions to fundamental biological research in the scenic Western Cape .

Key Responsibilities

• Lead the development and application of computational models to understand complex biological systems.
• Integrate diverse datasets, including genomics, transcriptomics, proteomics, and metabolomics, to build comprehensive system models.
• Design and oversee experimental validation studies to test model predictions.
• Mentor and guide a team of systems biologists and bioinformaticians.
• Collaborate with researchers across various disciplines to identify key biological questions addressable by systems biology approaches.
• Develop and implement novel computational methodologies and algorithms for systems-level analysis.
• Communicate research findings through publications in high-impact journals and presentations at international conferences.
• Contribute to grant proposals and secure funding for research initiatives.
• Ensure robust data management and reproducible research practices are maintained.

Requirements

• Ph.D. in Systems Biology, Computational Biology, Bioinformatics, Biophysics, or a related quantitative field.
• Minimum of 8 years of post-doctoral research experience with a focus on computational modeling of biological systems.
• Demonstrated expertise in building and analyzing large-scale biological networks and pathways.
• Proficiency in programming languages such as Python or R, and experience with modeling software (e.g., COPASI, CellDesigner, MATLAB).
• Strong understanding of molecular biology and cellular processes.
• Proven ability to lead research teams and manage complex projects.
• Excellent scientific communication and presentation skills.
• Experience with multi-omics data integration and analysis.
• Experience with high-performance computing environments is desirable.

Benefits

Our client offers a competitive salary, comprehensive benefits package including health, dental, and vision coverage, a generous retirement plan, and substantial support for professional development, conference participation, and further training. You will be part of a world-class research environment with state-of-the-art facilities and a collaborative ethos, dedicated to advancing the frontiers of biological understanding. This position is based in the vibrant academic setting of Stellenbosch, Western Cape .