Lead Epigenetics Researcher

Placements24; Cape Town; On-site; ZAR 1,200,000 - 2,000,000; Full time

Benefits offered by this job

Annual bonus

Medical and dental coverage

Stock option plan

Relocation assistance

Job summary

Placements24 in Cape Town seeks a Lead Epigenetics Researcher to spearhead innovative projects in epigenetic regulation and its links to health and disease. You will guide a dedicated team through conception to publication, translating discoveries into potential therapies, with opportunities to shape personalized medicine strategies in a dynamic biotech setting.

The role requires a Ph.D. with a strong publication record, 7+ years of experience in epigenetics, and proven leadership in research

Qualifications

• PhD with strong publication record in epigenetics or related field.
• Minimum 7 years post-doc or industry experience in epigenetics or related field.
• Demonstrated leadership in managing research teams and projects.

Responsibilities

• Design and execute epigenetic research projects (DNA methylation, histone mods, non-coding RNAs).
• Lead and mentor scientists, post-docs, and technicians.
• Develop and validate assays for detection of epigenetic marks.
• Analyze omics data (epigenomic, transcriptomic, proteomic) using statistical methods.
• Present findings at conferences and publish in journals.
• Collaborate with academia and industry partners; manage budgets and timelines.

Skills

Leadership

Bioinformatics

Data analysis

Communication

Education

Ph.D. in Molecular Biology / Genetics / Epigenetics

Tools

ChIP-seq

ATAC-seq

R

Python

Job description

About the Role

Our client, a pioneering biotechnology firm located in the scenic city of Cape Town , is actively seeking an experienced and visionary Lead Epigenetics Researcher. This critical role will spearhead our efforts in exploring the intricate mechanisms of epigenetic regulation and its impact on human health and disease. You will lead a dedicated team of scientists, driving ambitious research projects from conception through to publication, and translating discoveries into potential therapeutic interventions. This is an exceptional opportunity to shape the future of epigenetics research in Cape Town, Western Cape , and contribute to groundbreaking advancements in personalized medicine.

Key Responsibilities

Design and execute innovative research projects focused on understanding epigenetic modifications (e.g., DNA methylation, histone modifications, non-coding RNAs) and their role in cellular processes and disease pathogenesis. Lead and mentor a team of research scientists, post-doctoral fellows, and technicians, fostering a collaborative and high-performance research environment. Develop and validate novel assays and methodologies for the detection and quantification of epigenetic marks. Analyze complex biological datasets, including epigenomic (ChIP-seq, ATAC-seq, WGBS), transcriptomic, and proteomic data, using advanced computational and statistical approaches. Oversee the management of research projects, ensuring adherence to timelines, budgets, and scientific rigor. Present research findings at international conferences and publish in high-impact peer-reviewed journals. Collaborate with external academic institutions and industry partners to advance research goals. Ensure the ethical conduct of research and compliance with all relevant regulations. Contribute to the development of intellectual property and patent applications.

Requirements

Ph.D. in Molecular Biology, Genetics, Epigenetics, or a closely related field with a strong publication record. Minimum of 7 years of post-doctoral and/or industry research experience in epigenetics or a related field. Demonstrated leadership experience in managing research teams and projects. Extensive hands-on experience with various epigenetics experimental techniques and state-of-the-art technologies. Proficiency in bioinformatics tools and statistical software for analyzing large-scale omics data. Strong understanding of molecular biology principles, cellular signaling, and disease mechanisms. Excellent written and verbal communication skills, with a proven ability to present complex scientific information clearly and effectively. Track record of securing research grants or contributing significantly to grant applications. Experience in drug discovery or therapeutic development is a plus. Ability to think critically, solve complex problems, and drive innovation.

Benefits

Our client provides a highly competitive remuneration package, including a generous annual bonus, comprehensive medical and dental coverage, and a lucrative stock option plan. We offer significant opportunities for career advancement, participation in leading scientific conferences, and access to cutting-edge technologies and facilities in Cape Town . This role comes with the unique advantage of working in a beautiful coastal city, fostering a strong work-life balance. Relocation assistance to Western Cape will be provided for exceptional candidates.