Lead DMPK Scientist – ADME/PK Modeling & Strategy

Placements24; Randburg; On-site; ZAR 1,200,000 - 1,800,000; Full time

Job summary

Placements24 is seeking a globally recognized pharmaceutical research organization in Randburg to appoint a Principal Scientist to lead the DMPK group. The role requires deep expertise in ADME, PK/PD modeling, and oversight of in vitro and in vivo DMPK studies.

You will guide drug discovery programs and collaborate with chemists, pharmacologists and toxicologists to optimize candidates for development. The ideal candidate will demonstrate scientific excellence, strategic leadership, and the

Qualifications

• Extensive DMPK leadership experience in pharma R&D.
• Deep expertise in ADME and PK/PD modeling.
• Proven ability to manage multiple projects concurrently.

Responsibilities

• Lead DMPK group and projects in drug metabolism and pharmacokinetics.
• Design and oversee in vitro and in vivo DMPK studies.
• Interpret complex datasets to guide drug discovery and development.
• Collaborate with medicinal chemistry, pharmacology and toxicology teams.

Skills

DMPK experience

ADME studies

PK/PD modeling

Leadership

Job description

Placements24 is seeking a globally recognized pharmaceutical research organization in Randburg to appoint a Principal Scientist to lead the DMPK group. The role requires deep expertise in ADME, PK/PD modeling, and oversight of in vitro and in vivo DMPK studies.

You will guide drug discovery programs and collaborate with chemists, pharmacologists and toxicologists to optimize candidates for development. The ideal candidate will demonstrate scientific excellence, strategic leadership, and the