Clinical Pharmacologist

Placements24; Soweto; On-site; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Competitive salary

Medical, dental, vision coverage

Paid holidays

opportunities for publications

Job summary

Placements24 seeks a Clinical Pharmacologist to join a Soweto-based clinical development team, designing and overseeing PK/PD studies to characterize safety, efficacy, and pharmacokinetic/pharmacodynamic profiles of new drug candidates.

You will guide drug development strategies, ensure regulatory compliance, and contribute to trial progression while collaborating with clinical operations, regulatory affairs, and biostatistics. MD/PharmD with fellowship and 5+ years' experience are preferred.

Qualifications

• MD/PharmD with specialized fellowship in Clinical Pharmacology.
• 5+ years of experience in clinical pharmacology within pharma or academia.
• Strong PK/PD, drug metabolism, and DDI knowledge.
• Experience designing and analyzing clinical pharmacology studies.
• Familiarity with FDA/EMA/SAHPRA guidelines and regulatory submissions.

Responsibilities

• Design, develop, and oversee clinical pharmacology study protocols including Phase I.
• Provide leadership in PK/PD analysis and interpretation of trial data.
• Contribute to regulatory submissions by preparing clinical pharmacology sections of dossiers.
• Collaborate with internal teams and external experts.
• Stay current with literature, guidelines, and industry best practices.

Skills

PK/PD analysis

Regulatory compliance

Clinical trial design

Scientific writing

Cross-functional collaboration

Education

MD/PharmD with Clinical Pharmacology fellowship

Job description

About the Role

Our client is seeking a highly qualified Clinical Pharmacologist to join their clinical development team in Soweto . This critical role involves designing and overseeing clinical pharmacology studies to characterize the safety, efficacy, and pharmacokinetic/pharmacodynamic (PK/PD) profiles of new drug candidates. You will provide scientific expertise to guide drug development strategies, ensure regulatory compliance, and contribute to the successful progression of compounds through clinical trials. This position offers a rewarding opportunity to significantly influence the development of novel therapeutics.

Key Responsibilities

• Design, develop, and execute clinical pharmacology study protocols, including Phase I studies.
• Provide scientific leadership and input into the PK/PD analysis and interpretation of clinical trial data.
• Contribute to regulatory submissions by preparing relevant clinical pharmacology sections of dossiers.
• Collaborate with internal teams (e.g., clinical operations, regulatory affairs, biostatistics) and external experts.
• Stay abreast of the latest scientific literature, regulatory guidelines, and industry best practices in clinical pharmacology.
• Assess the impact of factors such as disease state, drug-drug interactions, and special populations on drug performance.

Requirements

• M.D. or Pharm.D. with specialized training/fellowship in Clinical Pharmacology or equivalent.
• Minimum of 5 years of experience in clinical pharmacology within the pharmaceutical industry or an academic setting.
• Strong understanding of pharmacokinetics (PK), pharmacodynamics (PD), drug metabolism, and drug-drug interactions.
• Experience with clinical trial design, execution, and data analysis.
• Familiarity with regulatory requirements and guidelines (e.g., FDA, EMA, SAHPRA) related to clinical pharmacology.
• Excellent scientific writing, presentation, and communication skills.

Benefits

• Highly competitive salary and comprehensive bonus structure.
• Full suite of benefits including medical, dental, and vision coverage.
• Generous vacation time and paid holidays.
• Opportunities for scientific publications and conference presentations.
• Be part of a leading organization dedicated to transforming patient lives through innovative medicines.