Biologics Process Development Lead

Placements24; Mtubatuba Local Municipality; On-site; ZAR 1,200,000 - 2,000,000; Full time

Benefits offered by this job

Medical, dental, and vision insurance

Retirement plan

Professional development

Job summary

Placements24 is seeking a Process Development Scientist specializing in biologics for its Richards Bay facility in KwaZulu-Natal. You will develop and optimize upstream and downstream bioprocesses, scale from lab to pilot to commercial, and work with cross-functional teams to ensure product quality and regulatory readiness.

The ideal candidate holds a PhD in a related field with at least 5 years of biologics process development experience, including cell culture and protein purification.

Qualifications

• PhD in a relevant field such as biochemical/chemical engineering or biotechnology.
• At least 5 years of hands-on process development experience for biologics.
• Proficient in mammalian cell culture, fermentation, or protein purification.
• Strong understanding of scale-up principles and technologies.
• Experience with process analytical technology (PAT) is desirable.
• Proficiency in statistical analysis and Design of Experiments (DoE).

Responsibilities

• Develop and optimize upstream and downstream processes for biologic drug substances.
• Scale up processes from lab to pilot plant and commercial scales.
• Characterize process performance and product quality attributes.
• Troubleshoot process deviations and implement effective solutions.
• Conduct process hazard analyses and implement safety measures.
• Collaborate with upstream/downstream manufacturing, analytical development, and regulatory affairs.
• Prepare technical reports and development summaries for regulatory filings.
• Stay current with industry trends and best practices in bioprocessing.
• Contribute to the intellectual property portfolio through invention disclosures.

Skills

Cell culture

Protein purification

Process development

DoE

PAT

Statistical analysis

Project management

Communication

Education

PhD in Biochemical Engineering / Chemical Engineering / Biotechnology

Job description

Placements24 is seeking a Process Development Scientist specializing in biologics for its Richards Bay facility in KwaZulu-Natal. You will develop and optimize upstream and downstream bioprocesses, scale from lab to pilot to commercial, and work with cross-functional teams to ensure product quality and regulatory readiness.

The ideal candidate holds a PhD in a related field with at least 5 years of biologics process development experience, including cell culture and protein purification.