VP, GI Cancer Clinical Development & Global Programs

OpenKrill; United States; Remote; USD 390,000 - 435,000; Full time

Benefits offered by this job

Paid Time Off

Holiday, and Sick Leave

Medical

Dental and Vision Plans

Short- and Long-Term Disability

Life/AD&D Coverage

FSA/HSA/Commute

Employee Stock Purchase Program

401(k) Plan with Erasca contribution

Stock options / equity grants

Job summary

Erasca, Inc. seeks a VP Clinical Development and Global Program Lead (GPL) for GI Cancers to provide medical leadership across pancreatic and colorectal cancer programs and collaborate with the CMO on portfolio strategy.

The role combines hands-on drug development with clinical oversight of studies and regulatory interactions. The role requires MD with oncology subspecialty, 8–10+ years in oncology development, and proven leadership in late-stage GI cancer programs, with a strong track record in

Qualifications

• MD degree with oncology subspecialty fellowship and board certification or eligibility.
• 8–10+ years of oncology clinical trial and drug development experience in pharma/biotech.
• Experience as clinical lead on late-stage GI cancers (colorectal/pancreatic).
• Experience leading regulatory filings and health authority interactions.
• Knowledge of clinical trial methodology and regulatory requirements.
• Ability to collaborate across functions in a matrixed environment.
• Executive leadership to influence stakeholders and strategic planning.
• Excellent writing and communication skills.

Responsibilities

• Provide medical direction to guide strategy for pancreatic and colorectal cancer programs.
• Lead the clinical development subteam for GI cancers.
• Design and implement novel clinical trials and endpoints.
• Lead study subteams and oversee safety/efficacy data.
• Develop registrational strategy and support regulatory filings.
• Serve as Medical lead on clinical programs and program teams.
• Partner with Drug Safety to assess safety profiles.
• Author clinical study documents and regulatory submissions.
• Contribute to publications and collaborate with thought leaders.
• Present at scientific, medical, and regulatory meetings.
• Maintain clinical and scientific expertise through literature and conferences.
• Participate in due diligence or business development.
• Hire, mentor, and develop medical directors and clinical scientists.
• Build relationships across Erasca, especially with R&D partners.
• Adhere to company values and regulatory requirements.

Skills

Clinical trial leadership

Oncology expertise

Cross-functional collaboration

Data-driven decision making

Medical writing

Education

MD degree with oncology subspecialty fellowship

Oncology board certification or eligibility

Job description

Erasca, Inc. seeks a VP Clinical Development and Global Program Lead (GPL) for GI Cancers to provide medical leadership across pancreatic and colorectal cancer programs and collaborate with the CMO on portfolio strategy.

The role combines hands-on drug development with clinical oversight of studies and regulatory interactions. The role requires MD with oncology subspecialty, 8–10+ years in oncology development, and proven leadership in late-stage GI cancer programs, with a strong track record in