Viral Vector Process Development Scientist II

Apollopros

South San Francisco (CA)

On-site

USD 55,000 - 78,000

Full time

46 hours ago
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Benefits offered by this job

Medical
Vision
Dental
401k

Job summary

Apollopros in South San Francisco, CA, is seeking a Scientist II to advance viral vector process development for LVV and AAV platforms. The role focuses on designing experiments, scaling upstream production, and applying DOE to optimize transfection conditions and harvest strategies.

The contract position emphasizes automation and high-throughput workflows, including liquid handling, Ambr systems, and analytical QC.

Qualifications

  • MS or PhD in Cell Biology, Molecular Biology, Virology, Biochemistry, Bioengineering, Genetics or related discipline.
  • Minimum of 3 years of laboratory research or industry experience.
  • Hands-on experience with mammalian cell culture and molecular biology techniques.
  • Direct experience with ex vivo CAR-T cell engineering using lentiviral vectors is required.

Responsibilities

  • Develop, optimize, and scale LVV upstream production platforms.
  • Design seed train expansion, shake flask production, and harvest activities.
  • Apply DOE to optimize transfection conditions and DNA-to-cell ratios.
  • Implement automated liquid-handling systems for high-throughput workflows.
  • Support downstream purification and analytical QC for LVV and AAV products.

Skills

Cell culture
Molecular biology
qPCR/ddPCR
Western blot
Data analysis
CAR-T engineering
Communication
Problem solving
Organization

Education

Cell Biology
Molecular Biology
Virology
Biochemistry
Bioengineering
Genetics

Job description

Apollopros in South San Francisco, CA, is seeking a Scientist II to advance viral vector process development for LVV and AAV platforms. The role focuses on designing experiments, scaling upstream production, and applying DOE to optimize transfection conditions and harvest strategies.

The contract position emphasizes automation and high-throughput workflows, including liquid handling, Ambr systems, and analytical QC.

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