Vertex Spring Co-Op 2027, Process Chemistry

Scorpion Therapeutics; Boston (MA); On-site; USD 34,000 - 48,000; Full time

Job summary

Vertex in Boston is seeking a Process Chemistry Co-Op to help develop scalable manufacturing processes for APIs in clinical trials. You’ll design and execute experiments using flow chemistry, photoredox catalysis, and high-throughput methods, and optimize reaction conditions.

You’ll analyze complex organic syntheses with NMR and HPLC, document thoroughly, review literature, interpret data, and present findings to the team.

Qualifications

• Currently pursuing a bachelor’s or master’s in Chemistry, Chemical Engineering, or related fields.
• Third-year student or above.
• Completion of organic chemistry coursework.
• Strong interest in synthesis and process chemistry.
• Good laboratory safety, organization, and communication skills.
• Eligible to work in the U.S.

Responsibilities

• Designing and executing experiments involving advanced techniques like flow chemistry, photoredox catalysis, and high-throughput methods.
• Optimizing reaction conditions.
• Analyzing complex organic syntheses.
• Utilizing analytical instruments such as NMR and HPLC.
• Collaborative experimentation, thorough documentation, literature review, data interpretation, and presenting findings to the team.

Skills

Process chemistry

Synthesis

Laboratory safety

Communication

Organization

Education

Chemistry / Chemical Engineering degree (BSc/MSc)

Tools

NMR

HPLC

Flow chemistry

Photoredox catalysis

High-throughput methods

Job description

Role

Process Chemistry Co-Op at Vertex, focused on developing scalable manufacturing processes for active pharmaceutical ingredients (APIs) in clinical trials.

Responsibilities

• Designing and executing experiments involving advanced techniques like flow chemistry, photoredox catalysis, and high-throughput methods
• Optimizing reaction conditions
• Analyzing complex organic syntheses
• Utilizing analytical instruments such as NMR and HPLC
• The role involves collaborative experimentation, thorough documentation, literature review, data interpretation, and presenting findings to the team

Requirements

• Currently pursuing a bachelor’s or master’s in Chemistry, Chemical Engineering, or related fields
• Third-year student or above
• Completion of organic chemistry coursework
• Strong interest in synthesis and process chemistry
• Good laboratory safety, organization, and communication skills
• Eligible to work in the U.S.
• Full-time availability from January to July 2027

Preferred qualifications

Prior research experience, familiarity with analytical techniques, and ability to analyze experimental data.

High-value specifics

Internship in process chemistry for biologics or small molecules, with emphasis on novel synthetic methods, process optimization, and collaboration within a fast-paced biotech environment.

Work setup

On-site in Boston with flexible work arrangements, full-time, paid at $25–$35/hour, with application deadline November 15, 2026.