Vertex Spring Co-Op 2027, Exploratory Chemistry

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 41,000 - 69,000; Full time

Benefits offered by this job

Gym access

Commuter benefits

Free breakfast

Career development

Social events

Location perks

National Intern Day

Job summary

Vertex Pharmaceuticals LLC in Boston invites students pursuing advanced degrees to join the Exploratory Chemistry Co-Op for six months. You''ll work on small molecule studies, gain hands-on experience, and collaborate with chemistry and biology teams to prepare reagents and run experiments.

This paid co-op offers mentorship, flexible on-site work, and opportunities to contribute to process development, data analysis, and reporting, with a January–July 2027 program and a $30–$50 hourly rate.

Qualifications

• Senior, Master's, PhD required.
• LC-MS familiarity expected.
• Experience with small molecule interactions and organic chemistry.
• Legal authorization to work in the United States; no sponsorship for internships/co-ops.
• Enrollment in an advanced degree if graduating before June 2027.
• Availability to work full-time, 40 hours/week, Jan–Jun 2027.

Responsibilities

• Prepare and organize chemical reagents and mixtures to support T1D small molecule studies.
• Support solubility and stability assessments under defined conditions in collaboration with PharmSci and AD.
• Process and interpret LC-MS data to evaluate identity, integrity, and degradation profiles.
• Document methods, observations and results clearly and reproducibly.
• Summarize findings and provide recommendations to optimize small molecule workflows for the T1D program.

Skills

Senior, Master's, PhD

LC-MS familiarity

Small molecule interactions

Organic chemistry

US work authorization

Advanced degree enrollment before June

Education

Chemical Engineering/Chemistry degree

Job description

Job Description

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab.

Why Vertex?

• Real Projects: You'll work on assignments that make a real impact, not just busy work.
• Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career.
• Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing.
• Inclusive Culture: Collaboration and inclusion are embedded in everything we do.
• Career Launchpad: Build skills, explore career paths, and get guidance for your future career.

Your Impact

The Vertex Exploratory Chemistry Co-Op, is a 6-month experiential training program for students currently working towards an advanced degree in Chemical Engineering, Chemistry, or other related fields. If you are passionate, collaborative, and growth-minded, a co-op at Vertex will help you gain meaningful experience in our PD Media Development functional areas and serve as a launchpad for your career.

The application deadline for this co-op is November 15th. Please note that Vertex reviews applications on a rolling basis and reserves the right to close this job posting prior to the listed deadline. Applicants can expect to receive an update about their application before or shortly after the application deadline.

What you will be doing:

The co-op will support small molecule studies by evaluating the solubility and stability of chemical mixtures. Their primary project will support the collaborative effort between PD and PharmSci to establish an understanding of mixture storage, stability and chemical compatibility, with the goal of generating data that supports process development and future manufacturing readiness.

The co-op will gain hands-on experience, working with both chemistry and biology teams to prepare reagents, run experiments, analyze data, and support related cell culture studies. This is an opportunity to learn how small molecules are formulated and applied in biologically relevant systems.

Key Responsibilities:

1. Prepare and organize chemical reagents and mixtures to support T1D small molecule studies.
2. Support solubility and stability assessments for selected chemical mixtures under defined conditions in collaboration with PharmSci and AD.
3. Process and interpret LC-MS data to evaluate compound identity, integrity, and degradation profiles.
4. Document experimental methods, observations, and results in a clear and reproducible manner.
5. Summarize findings and provide recommendations to support optimization of small molecule workflows for the T1D program.

Qualifications:

• Senior, Master's, PhD
• Chemical Engineering/Chemistry degree
• LC-MS familiarity
• Experience with small molecule interactions, organic chemistry, experiments to determine the solubility and stability of small molecules
• Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships/co-ops or entry level roles within this part of the organization.
• You must be enrolled in an advanced degree program if graduating before June 2027
• You must be available to work full-time, 40 hours per week from January - June 2027

Program Details:

• Full-time, paid co-op $30.00 - 50.00 USD/hour
• Program Dates: January - July 2027
• Application Deadline: November 15th, 2026

Benefits:

• Free 24/7 onsite gym access and free access to group exercise classes
• Subsidized commuter benefits- transit and parking
• Provided meals-free breakfast daily!
• Career development opportunities and events, including C Suite engagement
• Social events-both intern-only and company-wide
• Location-specific perks and extras!
• Recognition of National Intern Day

Our Ways of Working

• Flex Designation: On-Site - Boston
• Flex Eligibility Status: On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

This job posting is for a temporary role with a third-party agency partner that provides services to Vertex.