Variant Scientist

Tempus Labs, Inc.; Illinois; Hybrid; USD 85,000 - 100,000; Full time

Job summary

Tempus Labs, Inc. is seeking a Variant Scientist to collaborate with Clinical Teams on molecular reports for clinical utility.

You will classify somatic and germline variants for liquid biopsy, panel tests, and whole exome sequencing, and summarize results to generate high-quality clinical reports. The role requires an MS or PhD in Cancer Genetics or related field, with oncology experience preferred, excellent writing, and strict documentation adherence.

Qualifications

• MS or PhD in Cancer Genetics, Human Genetics, or Biological Sciences; oncology experience preferred.
• Strong writing and communication skills; meticulous attention to detail.
• Ability to follow formal documentation and SOPs; work both independently and in a team.

Responsibilities

• Accurately classify somatic and germline variants for liquid biopsy, panel tests, and whole exome sequencing.
• Use in-house tools to analyze clinical molecular data.
• Read and interpret scientific literature and curate findings for reports.
• Summarize genetic test results to generate high-quality clinical reports.
• Perform quality control to ensure reports comply with QA programs and SOPs.
• Support improvements for current assays and processes.
• Curate variants, genes, and diseases for clinical relevance.
• May train junior team members.

Skills

Scientific writing

Attention to detail

Communication

Teamwork

Education

MS/PhD in Cancer Genetics / Human Genetics / Biological Sciences

Tools

HGVS nomenclature

Genome browsers

In-house software tools

Job description

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. We are looking for a Variant Scientist who will work with our Clinical Teams on patient molecular reports for clinical utility. Please note: The Variant Science team works either Tuesday-Saturday or Sunday-Thursday.

Responsibilities

• Accurately classify somatic and germline variants for liquid biopsy, panel tests, and whole exome NGS sequencing.
• Utilize a variety of in-house software tools to analyze clinical molecular data.
• Read and interpret scientific literature and curate relevant findings in a clear, concise, and precise manner.
• Summarize somatic and inherited genetic test results to generate high quality clinical reports.
• Perform critical quality control functions for molecular reports that complies with quality management programs and standard operating procedures.
• Support improvements for current assays and processes.
• Curate variants, genes, and diseases for scientific and clinical relevance.
• May train junior team members.

Preferred Qualifications

• MS or PhD degree in Cancer Genetics, Human Genetics, or Biological Sciences Prior experience in a diagnostic laboratory, clinical report writing, and familiarity with human mutation databases, genome browsers, and HGVS nomenclature is preferred.
• Oncology experience strongly preferred
• Must have utmost attention to detail, excellent communication, and writing skills
• Ability to accurately follow formal documentation and protocols
• Ability to work in both an individual and group setting.
• Must be flexible and able to adjust priorities according to workload or management needs.

Illinois Pay Range: $85,000-100,000

CA/NY Pay Range: $85,000-100,000

The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience.

Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics. We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. We’re looking for people who can change the world. Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.