Variant Assessment Scientist I– Cardiology (REMOTE, USA)

Tempus AI, Inc.; California (MO); Hybrid; USD 100,000 - 112,000; Full time

Benefits offered by this job

Incentive compensation

Restricted stock units

Medical benefits

Job summary

Tempus AI, Inc. is seeking a Senior Variant Assessment Scientist to interpret molecular test results, review literature, and contribute to variant classification guidelines. You will help innovate methods for assessing sequence variants and support fast, accurate reporting.

The role involves guiding a collaborative clinical team, updating guidelines, and training new staff as the project expands within a highly adaptive, fast-paced environment.

Qualifications

• PhD or MD with expertise in molecular genetics, human genetics, molecular pathology or related field.
• MS in molecular biology or genetics with exceptional expertise may be considered.

Responsibilities

• Write and interpret molecular test results, including relevant medical literature reviews and summary.
• Participate in updating variant classification guidelines and developing gene-specific guidelines.
• Research novel ways to assess sequence variants.
• Manage and follow guidelines of variant pre-classification workflow to maximize reporting results within published turn-around times.
• Train new variant team members or clinical team.

Skills

Variant assessment

Literature review

Communication skills

Education

PhD/MD in molecular genetics

MS in molecular biology/genetics

Job description

Job Overview

Responsibilities include variant analysis of diagnostic molecular genetic test results; evaluation of published literature, clinical data and review of both functional and in silico data to provide accurate, thorough, and thoughtful clinical interpretation of results. Write research articles in collaboration with other medical professionals and colleagues outside and inside the organization, if data is relevant to the scientific community. Additional responsibilities as designated by supervisor/manager and/or with increasing seniority (Senior Variant Assessment Scientist).

Duties and Responsibilities

• Write and interpret molecular test results, including relevant medical literature reviews and summary.
• Participate in updating variant classification guidelines and developing gene specific classification guidelines.
• Research novel ways to assess sequence variants.
• Manage and follow guidelines of variant pre-classification workflow to maximize reporting results within published turn-around times.
• Train new variant team members or clinical team.

Education and Knowledge

PhD and/or MD with expertise in molecular genetics, human genetics, molecular pathology or related field. MS in molecular biology, genetics or related field with exceptional expertise and outstanding job performance may also be considered.

Technical Competencies

Thorough and ongoing knowledge of current theories and principles of human genetics. Excellent written and verbal communication skills to convey difficult information in a clear, kind, and respectful manner. Willingness and ability to work in and contribute to a fast-paced, highly collaborative environment.

Experience

Prior experience in variant assessment and reporting specialty preferred. Minimum +2 years of experience with variant assessment. Preferred: Cardiology experience preferred.

Industry experience

Industry experience $100,000-$112,000 The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience.

Benefits

Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

Equal Opportunity

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company's first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics. We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same - to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. We're looking for people who can change the world. Who question the status quo and don't shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We're looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.