NGS Scientist I

Tempus AI, Inc.; Chicago (IL); On-site; USD 75,000 - 95,000; Full time

Job summary

Tempus AI, Inc. is seeking a Scientist to support the development, optimization and validation of molecular assays and laboratory processes for deployment in our high-throughput clinical laboratory.

You will perform hands-on assay development for advanced molecular and NGS workflows, design qualification and validation studies, interpret data, troubleshoot issues, and mentor junior staff while collaborating across teams.

Qualifications

• Bachelor’s degree with 5+ years, or Master’s degree with 2+ years of relevant experience in molecular biology, assay development, or a related field.
• Strong analytical, troubleshooting, and experimental design skills.
• Ability to interpret results using scientific literature and SME input to refine experimental design
• Highly organized, detail-oriented, and committed to quality and accuracy.
• Proven ability to learn quickly and adapt to new processes, technologies, and workflows.
• Strong collaboration skills with the ability to lead across teams.
• Excellent oral and written communication skills.
• Experience working in dynamic environments with competing priorities and deadlines

Responsibilities

• Perform hands-on assay development for molecular and NGS-based workflows in a CAP/CLIA/NYSDOH regulated clinical laboratory.
• Design, execute, and analyze R&D experiments with strong attention to detail and scientific rigor.
• Design and execute qualification and validation studies for reagents, instruments, equipment, and methods to support clinical deployment.
• Interpret data, troubleshoot issues, and drive process improvements.
• Support automation and technology initiatives to improve laboratory workflows.
• Maintain clear and comprehensive documentation of methods, materials, and results.
• Train and mentor junior scientific staff and support implementation of new laboratory workflows as needed.
• Collaborate across cross-functional teams and provide scientific support in a matrixed environment.
• Communicate clearly and effectively with technical and non-technical stakeholders.
• Manage multiple priorities and adapt quickly in a fast-paced environment.
• Travel up to 10% as needed

Job description

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. At Tempus, we are leveraging the power of AI to transform clinical care. Our proprietary platform connects a vast ecosystem of real-world data to deliver intelligent, actionable insights that help physicians make more informed decisions and enable personalized treatment for patients. We are seeking a Scientist to support the development, optimization and validation of molecular assays and laboratory processes for deployment in our high-throughput clinical laboratory.

What You’ll Do

• Perform hands-on assay development for advanced molecular and NGS-based workflows in a CAP/CLIA/NYSDOH regulated clinical laboratory Design, execute, and analyze R&D experiments with strong attention to detail and scientific rigor Design and execute qualification and validation studies for reagents, instruments, equipment, and methods to support clinical deployment. Interpret data, troubleshoot issues, and drive process improvements. Support automation and technology initiatives to improve laboratory workflows. Maintain clear and comprehensive documentation of methods, materials, and results Train and mentor junior scientific staff and support implementation of new laboratory workflows as needed Collaborate across cross-functional teams and provide scientific support in a matrixed environment. Communicate clearly and effectively with technical and non-technical stakeholders. Manage multiple priorities and adapt quickly in a fast-paced environment. Travel up to 10% as needed

Qualifications

• Bachelor’s degree with 5+ years, or Master’s degree with 2+ years of relevant experience in molecular biology, assay development, or a related field.
• Strong analytical, troubleshooting, and experimental design skills.
• Ability to interpret results using scientific literature and SME input to refine experimental design
• Highly organized, detail-oriented, and committed to quality and accuracy.
• Proven ability to learn quickly and adapt to new processes, technologies, and workflows.
• Strong collaboration skills with the ability to lead across teams.
• Excellent oral and written communication skills.
• Experience working in dynamic environments with competing priorities and deadlines
• Ability to interpret results using scientific literature and SME input to refine experimental design

Preferred Technical Experience

• Hands-on experience with one or more of the following: DNA/RNA extraction and purification methods.
• PCR-based techniques, including PCR, qPCR, RT-PCR, and ddPCR.
• Nucleic acid manipulation, quantitation, and analysis.
• Assay troubleshooting, root cause analysis, and workflow optimization.
• Highly Desirable NGS library preparation, hybrid capture, and sequencing workflows.
• Experience with laboratory automation and liquid handling robotics
• Prior experience in a clinical laboratory environment
• Familiarity with LIMS and laboratory data systems

CHI: $75,000-$95,000 The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience.

Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer.

We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics. We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. We’re looking for people who can change the world. Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.