Theranostics Scientist Postdoc – Translational Research

Washington University in St. Louis; United States; On-site; USD 60,000 - 72,000; Full time

Job summary

Washington University in St. Louis seeks a scientist with strong training in synthetic chemistry, bioconjugation, and translational drug development to advance molecular imaging and therapeutic agents from bench discovery toward preclinical and clinical application.

The role centers on novel agent development, in vitro and in vivo studies, and initial human translation, with responsibilities spanning design, synthesis, purification, characterization, radiolabeling, and preclinical testing in a

Qualifications

• Education: Ph.D., M.D. or equivalent terminal degree.
• No specific work experience required for this position.
• No certifications or professional licenses required unless stated.

Responsibilities

• Designs, synthesizes, purifies, and characterizes novel chemical entities, chelators, linkers, and conjugates for theranostic applications.
• Develops and optimizes bioconjugation strategies for peptides, antibodies, proteins, and small molecules.
• Performs analytical characterization using HPLC, LC-MS, NMR, SEC, UV-Vis and related methods.
• Conducts in vitro evaluation of lead compounds, including stability, binding, pharmacologic, and functional assays.
• Participates in radiolabeling studies and radiopharmaceutical characterization.
• Designs and executes preclinical biodistribution, PK, target engagement, efficacy and safety studies.
• Analyzes data and prepares manuscripts, presentations, regulatory documents and grant reports.

Skills

Collaboration

Data Analysis

Data Interpretations

Experimentation

Laboratory Operations

Laboratory Techniques

Researching

Results Reporting

Scientific Writing

Education

Ph.D., M.D. or Equivalent Terminal or Doctoral Degree

PhD in chemistry, chemical biology, biological chemistry or biomedical engineering

Job description

Washington University in St. Louis seeks a scientist with strong training in synthetic chemistry, bioconjugation, and translational drug development to advance molecular imaging and therapeutic agents from bench discovery toward preclinical and clinical application.

The role centers on novel agent development, in vitro and in vivo studies, and initial human translation, with responsibilities spanning design, synthesis, purification, characterization, radiolabeling, and preclinical testing in a