Postdoc: Antibody Engineering & Molecular Imaging in Cancer

Washington University in St. Louis; St. Louis (MO); On-site; USD 52,000 - 68,000; Full time

Job summary

Washington University in St. Louis is seeking a highly motivated Postdoctoral Research Associate in the Pereira Laboratory, Department of Radiology, to join an NIH-funded translational oncology program.

The role focuses on antibody engineering, ADC development, molecular imaging, and theragnostic approaches, integrating computational biology with experimental work. You will design independent projects, analyze multi-omics data, mentor trainees, and contribute to a collaborative lab environment

Qualifications

• Ph.D. in Cancer Biology, Chemical Biology, Biochemistry, Biomedical Engineering, Pharmaceutical Sciences, Immunology, Bioinformatics, Computational Biology, Chemistry, or a related discipline.
• Experience in antibody engineering, ADC development, protein conjugation, or chemical biology; spatial transcriptomics, single-cell genomics, bioinformatics, or computational biology; molecular imaging, radiochemistry, or image analysis.
• Strong written and verbal communication skills, scientific independence, and enthusiasm for interdisciplinary research are essential.
• Candidates with expertise in either experimental or computational research (and willingness to develop complementary skills) are encouraged to apply.

Responsibilities

• Design and execute independent research projects focused on antibody engineering, ADC development, molecular imaging, and theragnostic agents.
• Develop and evaluate novel antibody conjugates using molecular, cellular, biochemical, and in vivo approaches.
• Perform cancer biology studies using cell lines, patient-derived models, and mouse models.
• Analyze and integrate molecular imaging, spatial transcriptomics, and other multi-omics datasets to identify biomarkers and mechanisms of therapeutic response.
• Develop computational workflows for spatial biology and imaging data analysis using R, Python, or related tools.
• Design experiments, analyze data, troubleshoot technical challenges, and critically interpret scientific findings.
• Organize, manage, and integrate experimental datasets in compliance with laboratory, institutional, and NIH data management and reproducibility standards.
• Prepare manuscripts, fellowship applications, grant proposals, and present research at national and international scientific meetings.
• Mentor graduate students and other laboratory trainees while contributing to a collaborative research environment.

Skills

Antibody engineering

ADC development

Spatial transcriptomics

Computational biology

Molecular imaging

Education

Ph.D. in Cancer Biology or related field

Job description

Washington University in St. Louis is seeking a highly motivated Postdoctoral Research Associate in the Pereira Laboratory, Department of Radiology, to join an NIH-funded translational oncology program.

The role focuses on antibody engineering, ADC development, molecular imaging, and theragnostic approaches, integrating computational biology with experimental work. You will design independent projects, analyze multi-omics data, mentor trainees, and contribute to a collaborative lab environment