Technical Development Scientist / Engineer

Genentech; South San Francisco (CA); On-site; USD 84,000 - 157,000; Full time

Job summary

An established industry player is seeking a motivated individual to join their Process Virology team. This role involves conducting critical virus clearance studies and optimizing purification processes. The ideal candidate will have a strong background in biology or a related field, with hands-on experience in purification development and analytical skills. Join a forward-thinking company dedicated to advancing healthcare and making a positive impact on patients' lives. This is an exciting opportunity to contribute to innovative therapies in a collaborative team environment.

Qualifications

• 2+ years experience in healthcare/biotech/pharmaceutical industry.
• Experience in purification development and virus clearance preferred.
• Strong work ethic and ability to multitask effectively.

Responsibilities

• Conduct virus clearance studies and small-scale purification processes.
• Document and analyze lab scale chromatography and filtration.
• Maintain cell lines and prepare media and buffers.

Skills

Analytical Skills

Technical Troubleshooting

Communication Skills

Detail-oriented

Education

BS/MS in Biology

BS/MS in Molecular Biology

BS/MS in Biochemistry

BS/MS in Virology

BS/MS in Chemical Engineering

Tools

Chromatography

qPCR Assays

Cell Culture

Virus Clearance Techniques

Job description

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche!

As part of Pharma Technical Development (PTD) our organization is committed to deliver the Pharma ambitions by bringing game-changing therapies from clinical phase I into the market to serve every patient, every day. Our core business is to develop safe, innovative and effective drugs using cutting edge technologies for manufacturing process (Drug Substance and Drug Product), clinical supply, formulation, device, packaging, and analytical development.

Together with our partners, Global Biologics Bioprocess Development develops robust, efficient, and sustainable bioprocesses including Cell Line & Media Development, Cell Culture & Fermentation, and Purification Development.

The Opportunity

We are looking for a highly motivated candidate to join the Process Virology team in Purification Development. The candidate will be working as part of a team in the laboratory conducting virus clearance studies. Responsibilities will include performing small-scale purification processes (e.g. chromatography and filtration), cell-based infectivity assays, virus nucleic acid purification and quantification, equipment qualification, and documentation of results (e.g. protocols, lab notebooks, and reports). The candidate will also be responsible for new technology development and process optimization as it benefits Genentech current and future purification platforms. This work will also include preparation of buffers, cell culture media, and cell culture maintenance. The candidate must be able to perform multiple laboratory duties, follow lab quality standards and safety compliance. The selected individual is expected to work independently as well as in a team setting to design and execute experiments and strategies.

Main responsibilities

• Execution, documentation and analysis of lab scale chromatography, virus inactivation, and filtration

• Execution, documentation and analysis of cell-based virus infectivity assays and qPCR assays

• Maintain cell lines, prepare media and buffers, and maintain related equipment

• Present results to teams

• Author technical or validation study reports

• Work collaboratively with other members of the Process Virology Team and Purification Development

Who you are

• BS/MS degree in biology, molecular biology, biochemistry, virology, chemical engineering or a related field

• 2+ years relevant experience in healthcare/ biotech/ pharmaceutical industry. Experience in purification development, virus clearance, biopharmaceutical manufacturing, assay development, and/or validation is preferred

• Able to apply analytical skills and judgment in assessing the quality of assay data and assay performance

• Experience with or understanding of equipment qualification and validation requirements is also desirable

• Must have a strong work ethic, must be self-motivated, flexible, able to multitask, and meet timelines efficiently and productively

• Detail-oriented, customer-focused, with excellent organizational skills

• Strong focus on technical troubleshooting skills

• Able to work independently as well as in a team environment

• Strong verbal communication, writing, and listening skills, as well as interpersonal skills required

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $84,600 to $157,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.