T Cell Therapy Scientist — Engineered Immunity & Flow

F. Hoffmann-La Roche AG; South San Francisco (CA); On-site; USD 103,000 - 192,000; Full time

Benefits offered by this job

Relocation benefits

Benefits detailed in job posting

Job summary

Genentech seeks a scientist to develop novel cell therapies, focusing on T cell biology, primary culture, and immune cell engineering. You will work across diverse teams to advance the cell therapy pipeline and contribute to scientific strategy.

The role requires hands-on experience with T cells, advanced flow cytometry, and data-driven decision making, with strong collaboration and communication skills across multidisciplinary groups.

Qualifications

• PhD/MD/DVM or equivalent with several years of relevant experience.
• Hands-on T cell isolation, activation, culture and expansion.
• Deep knowledge of T cell biology and memory.
• Advanced multiparameter flow cytometry and data interpretation.
• Experience engineering immune cells using viral and non-viral methods.
• Ability to design rigorous experiments and analyze multidimensional data.
• Strong communication and cross-team collaboration skills.

Responsibilities

• Engineer primary T cells and other relevant cell types.
• Develop and apply multiparameter flow cytometry assays to characterize T cells.
• Evaluate engineered T cells with proliferation, cytokine, and persistence assays.
• Analyze datasets and guide experimental strategy.
• Collaborate with research, translational, computational, and process development teams.
• Maintain thorough experimental records and communicate results clearly.

Skills

T cell biology

Primary T cell culture

Multiparameter flow cytometry

Immune cell engineering

Education

PhD/MD/DVM or equivalent

Tools

Flow cytometry equipment

Viral and non-viral gene delivery methods

Job description

Genentech seeks a scientist to develop novel cell therapies, focusing on T cell biology, primary culture, and immune cell engineering. You will work across diverse teams to advance the cell therapy pipeline and contribute to scientific strategy.

The role requires hands-on experience with T cells, advanced flow cytometry, and data-driven decision making, with strong collaboration and communication skills across multidisciplinary groups.