SVP, Head of Clinical Operations

Liquidia Corporation; Morrisville (NC); On-site; USD 300,000 - 460,000; Full time

Job summary

Liquidia is seeking a dynamic and experienced Senior Vice President, Head of Clinical Operations, to lead the strategic and operational execution of our expanding clinical pipeline and portfolio in serious pulmonary and vascular diseases.

The ideal candidate will be a hands‑on leader with deep expertise in respiratory clinical development and a proven track record of overseeing multiple programs from early to late phase in the US and globally.

Qualifications

• 15+ years in clinical operations leadership in biotech or pharma.
• Proven track record overseeing 5+ Phase I–IV programs.
• Experience leading multi-regional/global trials (US, EU, APAC).
• Deep understanding of pulmonary/respiratory areas.
• Strong vendor management and budgeting skills.

Responsibilities

• Define long-term vision and operating model for Clinical Operations.
• Build and mentor a high-performing, scalable team.
• Collaborate with R&D leadership across Clinical Dev, Regulatory, CMC and Quality.
• Oversee global program planning, budgeting, and execution to GCP standards.
• Drive process improvements and vendor relationships for quality and efficiency.

Skills

Leadership

Clinical operations

Strategic planning

Budgeting

Vendor management

Education

Bachelor's degree

Job description

Liquidia is deeply passionate and committed to the discovery, engineering, and development required to bring novel therapies to patients who need them most, and to the healthcare providers who care for them. Our current drive is toward improving the treatment of pulmonary hypertension (PH). We will continue to combine our proprietary, innovative PRINT® Technology with new and established medications, offering the potential for both better precision and improved clinical outcomes. Our team members include some of the industry’s top scientists, clinicians, business strategists, engineers, and pharmaceutical executives. We work together to help people lead longer, healthier, and happier lives.

Job Summary

Liquidia is seeking a dynamic and experienced Senior Vice President, Head of Clinical Operations, to lead the strategic and operational execution of our expanding clinical pipeline and portfolio in serious pulmonary and vascular diseases. The ideal candidate will be a hands‑on leader with deep expertise in respiratory clinical development and a proven track record of overseeing multiple programs from early to late phase in the US and globally.

Reporting to the Chief Development Officer of Clinical, this individual will help shape the future strategy, structure and culture of Clinical Operations, influence corporate strategy and lead innovative global clinical programs. The S/VP will manage a growing internal team and a network of external partners and consultants, ensuring flawless clinical execution across all active and planned programs.

Responsibilities

• Define and implement the long‑term vision, organizational design, and operating model for Clinical Operations.
• Build, lead, and mentor a high‑performing team capable of scaling with company growth.
• Serve as a trusted member of the R&D leadership team, collaborating closely with Clinical Development, Regulatory, CMC, Clinical Quality and Commercial functions and colleagues.
• Serve as a strategic advisor to the executive leadership team
• Evaluate and implement emerging technologies and innovative trial methodologies to improve efficiency and patient experience.

Clinical Execution

• Oversee planning, execution, and delivery of multiple concurrent clinical programs across different stages of development including supporting investigator‑led and post‑marketing studies
• Lead global study expansion, including country/region selection, feasibility, site activation, and oversight of regional CROs and vendors; ensure compliance with local regulations, ethics committee requirements, import/export (IP, samples), and data privacy laws.
• Drive operational excellence, ensuring programs are delivered on time, within budget, and in compliance with global GCP standards.
• Optimize vendor relationships (CROs, central labs, data management, etc.) for quality, accountability, and efficiency.
• Ensure consistency across and within clinical programs.

Operational Oversight

• Develop and manage departmental budgets, forecasts, and resource plans.
• Implement metrics and dashboards to monitor performance, quality, and risk across studies.
• Champion process improvement and innovation, introducing scalable tools and best practices.

Cross‑Functional Collaboration

• Partner with Clinical Development, Regulatory Affairs, Safety and Pharmacovigilance Clinical Quality and Program Management to align operational strategy with corporate goals.
• Contribute to program governance, study design input, and clinical strategy discussions.
• Represent Clinical Operations in regulatory and partner interactions as needed.

Requirements

• Bachelor’s degree required, preferably in a related field.
• 15+ years of progressive experience in clinical operations leadership within biotech or pharma.
• Demonstrated success overseeing 5+ clinical programs (Phase I–IV) simultaneously.
• Proven experience leading multi‑regional/global trials (e.g., U.S., EU, and APAC), including start‑up through close‑out.
• Deep understanding of pulmonary/respiratory therapeutic areas required.
• Proven ability to scale teams and establish efficient organizational structures.
• Strong vendor management, budgeting, and operational governance experience.
• Collaborative, decisive leader with exceptional communication and change management skills.
• Based in or willing to travel frequently to the Raleigh–Durham (RTP) area preferred; or East Coast candidates.

Liquidia offers a competitive compensation package as well as a comprehensive benefits package that includes Medical, Dental, Vision, STD, LTD, 401(k) Savings Retirement Plan, ESPP, and more!

Liquidia is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. Reasonable accommodation may be made to enable qualified individuals with disabilities to perform the essential functions of this position.