Strategic Projects Lead - Engineering

AfterQuery; San Francisco (CA); On-site; USD 180,000 - 230,000; Full time

Benefits offered by this job

Health Insurance

401(k) with Employer Match

Daily Meals: UberEats stipend

Monthly Wellness Stipend

Job summary

AfterQuery, a San Francisco‑based applied AI research lab, seeks a senior engineer to architect core data infrastructure powering foundation-model development. You will work with leading AI labs to deliver scalable data solutions and directly influence model training and evaluation.

The role demands deep chemical/biomedical life-sciences expertise, proven leadership, and a passion for AI with an entrepreneurial mindset.

Qualifications

• 3+ years in chemical/biomedical/life-sciences engineering roles at top companies, labs, or hospitals.
• Background in chemical process design or related life-sciences engineering.
• Deep understanding of chemistry/biology fundamentals with quantitative reasoning.
• High agency and ability to define problems with minimal direction in ambiguity.
• Demonstrated leadership and strong communication abilities.
• Genuine passion for AI and entrepreneurial inclination.
• Evidence of competitive achievements (patents, publications, etc.).

Responsibilities

• Project and client management with AI organizations to build data solutions and drive revenue.
• Lead and coordinate specialized teams across domains to deliver outputs at scale.
• Design dataset specifications influencing model evaluation and improvements.
• Own critical projects end-to-end from scoping to shipping in a fast-paced environment.
• Support cross-functional business initiatives across multiple units.

Skills

Chemical engineering

Biomedical engineering

Life sciences

Leadership

AI & data solutions

Communication

Entrepreneurial mindset

Patents/Publications

Education

MS/PhD/MD in related field

Tools

Python

Aspen Plus

MATLAB

COMSOL

Job description

About AfterQuery

AfterQuery is an applied research lab curating data solutions for foundation model development. We serve every frontier AI lab with the mission of delivering the best data to power the best models. In doing so, we can make expertise that once took a lifetime to build available to anyone who needs it.

Our customers are the ones building the foundation models themselves and our work sits directly in the loop of how those systems improve. This is a rare opportunity to join a company at a defining moment in AI. Forbes reported that we could be YC's fastest unicorn, reportedly raising at a $3.2 billion valuation. We're based in San Francisco and backed by leading investors including Altos Ventures, BoxGroup, and Y Combinator and angels from Google DeepMind, OpenAI, Anthropic, Meta Superintelligence Labs, and Microsoft AI.

Why Apply

Massive Opportunity: Forbes reported that we could be YC's fastest unicorn, reportedly raising at a $3.2 billion valuation, and we're not slowing down.

Founding Impact: You will own and architect core infrastructure systems that power our platform from the ground up.

Equity & Growth: Competitive salary and meaningful equity. As we scale, you’ll have the opportunity to shape the engineering organization and lead major technical initiatives.

Strong Team: Our founding team has experience from Citadel Securities, Meta, Google, Silver Lake, and Morgan Stanley — work alongside world‑class engineers and researchers.

Key Responsibilities

Project and client management: Work with the world’s leading AI organizations to build next‑generation data solutions that push the limits of model capability, while directly driving revenue.

Manage expert teams across domains: Lead and coordinate highly specialized contributors across fields like finance, software engineering, law, and more to create high‑quality outputs at scale.

Shape how AI systems are trained: Design dataset specifications that directly influence how frontier models are evaluated and improved. Your taste and judgement will shape what foundation models become.

Drive high‑impact execution end‑to‑end: Own critical projects from idea to delivery. From scoping, executing, iterating, and shipping in a fast‑moving, high‑stakes environment, you will touch it all.

Gain top tier operational experience: Support the team across a range of operational initiatives that will directly contribute to the future of AfterQuery. You will work across multiple parts of the business in the same week, ranging from building, analyzing, coordinating, and executing where needed most.

Required Qualifications

• 3+ years of experience in chemical engineering, biomedical engineering, biotech, pharma, or related process/life‑sciences engineering roles at top companies, research labs, or clinical/hospital settings
• Background in chemical process design, biomedical devices, drug development, or related life‑sciences engineering
• Deep understanding of chemistry and biology fundamentals along with quantitative process- and systems‑level reasoning
• High agency and strong work ethic; comfort defining problems and thriving with minimal direction in ambiguous situations
• Demonstrated leadership excellence and strong communication abilities
• Genuine passion for AI and an entrepreneurial inclination
• Demonstrated competitive success (e.g., patents, publications, board/licensing exams, or top‑tier academic/professional achievement)

Preferred Qualifications

• Python proficiency or experience with simulation and analysis tools (e.g., Aspen Plus, MATLAB, COMSOL, bioinformatics pipelines)
• Advanced degree (MS/PhD/MD) in chemical engineering, biomedical engineering, chemistry, or a related field
• Experience in the pharma, biotech, or medical‑device industry
• Familiarity with Claude Code or similar AI‑assisted workflows
• Experience across multiple engineering or life‑sciences domain

Company Benefits (For Eligible Employees)

• Health Insurance: Medical, Vision, Dental
• 401(k) with Employer Match
• Daily Meals: Daily UberEats Stipend
• Monthly Wellness Stipend

We are an equal opportunity employer committed to providing a workplace free from discrimination and harassment. Employment decisions are made without regard to legally protected characteristics under applicable federal, state, or local law.

We comply with applicable pay transparency requirements and provide compensation ranges based on the position, qualifications, experience, and other relevant factors. Reasonable accommodations are available to qualified individuals with disabilities and for sincerely held religious beliefs, as required by law. This job description is intended to describe the general nature and level of work performed and is not an exhaustive list of all duties, responsibilities, qualifications, or working conditions associated with the position. We reserve the right to modify this job description as business needs change.