Stem Cell Research Associate II – MPN Consortium

Mount Sinai; New York (NY); On-site; USD 66,000 - 85,000; Full time

Job summary

Mount Sinai's Tisch Cancer Center and the Division of Hematology/Medical Oncology invite applications for an Associate Researcher to join the MPNR-C led by Dr. Ronald Hoffman.

The lab studies stem cell biology in myeloproliferative neoplasms using patient samples, iPSC models, and advanced cellular and molecular techniques. The successful candidate will perform lab work in support of basic, translational, and clinical research studies, analyze data, maintain records, and contribute to SOPs and

Qualifications

• Bachelor's degree in sciences or related field or equivalent experience.
• 2 years in a research environment or 1 year plus Masters Degree in sciences or related field.
• Experience with human primary cell culture and hematopoietic stem cells preferred.
• Induced pluripotent stem cell culture experience highly desirable.
• Working knowledge of flow cytometry and basic molecular biology techniques (nucleic acid isolation, PCR, protein analysis).
• Experience with animal research and mouse handling.
• Excellent organizational, analytical, and problem-solving skills.
• Strong verbal, written, and interpersonal communication skills.
• Ability to maintain detailed experimental records and work independently and collaboratively.
• Demonstrated commitment to scientific research and ability to manage multiple projects in a fast-paced lab.

Responsibilities

• Under direct supervision, conducts routine and standardized experiments using lab techniques.
• Prepares culture media, reagents, and materials for cell culture and procedures.
• Isolates and processes primary patient samples using density gradient centrifugation and other methods.
• Performs in vitro cell culture, cell-based assays, and maintains human primary cells and iPSC cultures.
• Assists with animal studies, including cell preparation, transplantation, and tissue harvesting from xenografted mice.
• Performs sample preparation, staining, and flow cytometric analyses.
• Conducts basic molecular biology procedures including DNA, RNA, and protein isolation, qPCR, genotyping, and Western blot.
• Maintains meticulous experimental records and lab documentation.
• Analyzes and assists in data interpretation; assists in preparing SOPs, figures, presentations, and manuscripts.
• Performs other related duties as assigned.

Skills

Flow cytometry

Molecular biology

Cell culture

iPSC culture

Animal handling

Genotyping

PCR

Western blot

Nucleic acid isolation

Education

Bachelor's degree in sciences or related field

Masters degree in sciences or related field

Tools

Flow cytometer

PCR equipment

Western blot apparatus

Job description

Mount Sinai's Tisch Cancer Center and the Division of Hematology/Medical Oncology invite applications for an Associate Researcher to join the MPNR-C led by Dr. Ronald Hoffman.

The lab studies stem cell biology in myeloproliferative neoplasms using patient samples, iPSC models, and advanced cellular and molecular techniques. The successful candidate will perform lab work in support of basic, translational, and clinical research studies, analyze data, maintain records, and contribute to SOPs and