Sr. Staff Scientist

Roche; Los Angeles (CA); On-site; USD 127,000 - 237,000; Full time

Job summary

Roche seeks a Sr. Staff Scientist specializing in Chemistry and NanoTechnology to lead R&D efforts for their ePlex system. Ideal candidates will have a PhD and extensive experience in diagnostics, focusing on material sciences and analytical techniques. This role includes mentoring junior staff and driving innovation in a collaborative environment.

Qualifications

• 6+ years of R&D experience in diagnostics or biotechnology.
• Experience with design control and change management.
• Ability to lead technical studies and mentor junior scientists.

Responsibilities

• Provide expert technical leadership for reagent and surface preparation strategies.
• Design experiments to support product development and innovation.
• Lead cross-functional teams to execute technical studies.

Skills

Material Sciences

Analytical Chemistry

Surface Chemistry

Education

PhD in Chemistry, Chemical Engineering, Material Sciences or related degree

Tools

NMR

GC-MS

LC-MS

XPS

DSC

Job description

Join to apply for the Sr. Staff Scientist role at Roche

Join to apply for the Sr. Staff Scientist role at Roche

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

The Chemistry and NanoTechnology subject matter expert and manager, will serve concept-to-market and sustaining efforts for the ePlex digital microfluidics platform within the Consumable and Assay Technology team. They will provide technical, strategic and hands-on expertise for on-market support and enhancement projects and for invention and development of new and enhanced nanomaterials, surfaces, polymers and reagents for sample to answer IVD products. They will identify and create analytical chemistry methods and drive their application through internal and external collaboration, to ensure critical quality attributes are understood and controlled. This individual will provide technical leadership to internal and external resources, vendors, suppliers and service organizations. They will drive troubleshooting and root cause analysis, creation and maintenance of input and output specifications, concept and feasibility activities, prototyping, testing, and transfer to manufacturing. Spearhead efforts in the optimization and design of material surfaces at the interface or biochemical, organic chemistry and electrochemical technology. This includes meticulous control over (bio)chemical modification, surface energy, minimization of non-specific adsorption phenomena, chemical stability, all crucial for the performance and reliability of sophisticated consumables. The successful candidate will play a central role in driving the successful enhancement, support and development, scale-up, improvement and market introduction of novel, high-performance consumables, directly contributing to Roche's continued leadership in the diagnostics space.

The Opportunity:

Your responsibilities in this role will include:

• Provide expert technical leadership and research and development strategies for the design, development, and implementation of surface preparation strategies, reagent development for chemicals, polymers and nanomaterials intended for complex life sciences and diagnostic consumable application
• Design and conduct experiments to support product development and product improvement
• Contribute to and drive innovation initiatives including patent applications and trade secrets
• Drive the synthetic manipulation of material surfaces at a molecular level to precisely engineer surface energy characteristics and effectively mitigate non-specific adsorption of critical biomolecules, ensuring optimal performance and minimizing background noise in downstream applications
• Lead cross-functional teams in the development and execution of comprehensive technical studies that align with product requirements, manufacturing feasibility, and commercialization timelines for intricate consumables
• Develop advanced surface analysis and characterization using a diverse range of analytical techniques (e.g.,NMR, GC-MS, LC-MS, XPS, DSC, ToF-SIMS, AFM, HPLC, mass spec, contact angle goniometry, ellipsometry) to thoroughly understand surface composition, morphology, and chemical properties, reagent stability and to establish critical structure- property relationships
• Serve as a subject matter expert in surface chemistry, analytical sciences and nano technology and self assembled monolayers, providing deep technical insights and guidance to problem-solving and troubleshooting efforts within complex, interconnected, and multidisciplinary system environments, effectively identifying root causes and implementing sustainable solutions related to surface performance
• Mentor and guide junior scientists and engineers, fostering a culture of technical excellence and continuous learning
  
  

Who you are:

• Minimum of PhD degree in Chemistry, Chemical Engineering, Material Sciences or related degree. with 6+years (8+ preferred) of R and D or trouble shooting and technical leadership experience in diagnostics, chemical or biotechnology companies
• Motivated to contribute in designing, developing, and sustaining medical or in-vitro diagnostics consumables while working within an ISO 13485/GMP compliant environment
• Ability to utilize root cause analysis techniques for (bio)chemical components and interface with mechanical parts and assemblies
• Experience with a mature product development process under design control and change management
• Experience with interdisciplinary innovation (chemistry, materials, biotechnology, fabricated components) and integration
  
  

Relocation benefits are not available for this posting

The expected salary range for this position based on the primary location of California is $127,300.00 - $236,300.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits
Who we are

GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMark’s ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California.

GenMark is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

Seniority level

• Seniority level

  Associate

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Science, and Engineering

• Industries

  Pharmaceutical Manufacturing, Biotechnology Research, and Medical Equipment Manufacturing

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