Sr. Scientist- PKDM-BA (Immunoassay)

Amgen Inc. (IR); Thousand Oaks (CA); On-site; USD 130,000 - 176,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental, vision benefits

Stock-based incentives

Annual bonus program

Job summary

Amgen in Thousand Oaks, CA seeks a Sr. Scientist – Non-Regulated Immunoassays to support PKDM programs with hands-on immunoassay development and validation.

You will lead cross-functional efforts to develop and qualify assays across ELISA, MSD/ECL, Gyrolab, Quanterix, and AlphaLISA, generating robust data for program decisions. The role emphasizes strong laboratory expertise, troubleshooting, data analysis, and collaboration across Discovery Research, Precision Medicine, Translational Safety,

Qualifications

• PhD/PharmD/MD or equivalent with post-doc experience.
• Master’s degree with three years of scientific experience considered.
• Bachelor’s degree with five years of scientific experience considered.
• Industry experience in immunoassay development is preferred.
• Strong analytical and data interpretation skills.

Responsibilities

• Develop, qualify, validate, and execute non-regulated immunoassays for PK measurements.
• Perform sample analysis across ELISA, MSD/ECL, Gyrolab, Quanterix, and AlphaLISA.
• Design experiments, analyze results, troubleshoot issues, and implement improvements.
• Generate high-quality, reproducible data adhering to scientific standards.
• Lead assay transfer and method qualification activities to support programs.
• Interpret results and communicate findings via reports and presentations.
• Collaborate with Discovery Research, Precision Medicine, and Translational Safety.
• Maintain thorough laboratory records and data management practices.
• Evaluate new immunoassay technologies and methodologies for potential adoption.
• Support instrument maintenance, reagent qualification, and inventory management.

Skills

Immunoassay development

Non-regulated immunoassays

Bioanalytical data analysis

Cross-functional collaboration

Laboratory troubleshooting

Education

PhD/PharmD/MD

Master’s degree + 3 years science

Bachelor’s degree + 5 years science

Tools

ELISA

MSD/ECL

GyroLab

Quanterix

AlphaLISA

Job description

Career Category Scientific Job Description

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr. Scientist- PKDM-BA (Immunoassay)

What you will do Let's do this. Let's change the world. Amgen is seeking a motivated and scientifically rigorous Senior Scientist – Non-Regulated Immunoassays to join the PKDM organization at our Thousand Oaks, California site. This position will support biologics programs through the development, qualification, validation, and execution of non-regulated immunoassays used for pharmacokinetic and soluble target protein measurements. The successful candidate will bring strong hands-on laboratory expertise and a proven track record of developing and executing immunoassays across multiple platforms. This individual will work collaboratively with cross-functional partners to generate high-quality bioanalytical data that supports key program decisions throughout drug development. This role is highly laboratory-focused and requires extensive experience designing, troubleshooting, validating, and performing immunoassays in a fast-paced research environment.

Responsibilities Include:

• Develop, optimize, qualify, validate, and execute non-regulated immunoassays supporting pharmacokinetic and soluble target protein measurements.
• Perform sample analysis using a variety of immunoassay platforms including ELISA, MSD/ECL, Gyrolab, Quanterix, AlphaLISA, and other relevant technologies.
• Independently design experiments, analyze results, troubleshoot technical issues, and implement assay improvements.
• Generate high-quality, reproducible data while adhering to established scientific standards and laboratory procedures.
• Perform assay transfer, method qualification, and validation activities as required to support program objectives.
• Analyze and interpret experimental results and communicate findings through technical reports, presentations, and team discussions.
• Collaborate with scientists across Discovery Research, Precision Medicine, Translational Safety and Risk Sciences, and other functional areas.
• Maintain accurate laboratory records, experimental documentation, and data management practices.
• Contribute to evaluation and implementation of new immunoassay technologies and methodologies.
• Support laboratory operations including instrument maintenance, reagent qualification, inventory management, and continuous process improvements.

What we expect of you

Basic Qualifications:

• Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] OR Master’s degree and 3 years of scientific experience OR Bachelor’s degree and 5 years of scientific experience

Preferred Qualifications:

• Master's degree in Immunology, Biochemistry, Bioanalytical Sciences, Pharmaceutical Sciences, or related scientific discipline
• 3–5 years of industry or contract research organization experience in immunoassay development and bioanalysis
• Demonstrated experience developing, qualifying, validating, and executing non-regulated immunoassays
• Strong hands-on expertise with immunoassay platforms including ELISA, MSD/ECL, Gyrolab, Quanterix, AlphaLISA, or related technologies
• Experience supporting pharmacokinetic and soluble target protein measurements for biologics programs
• Proven ability to independently conduct laboratory experiments, troubleshoot assay performance issues, and analyze complex datasets
• Strong understanding of immunoassay principles, assay optimization, and bioanalytical best practices
• Experience performing sample analysis and generating high-quality bioanalytical data in a regulated or non-regulated research environment
• Excellent organizational skills and attention to detail
• Strong written and verbal communication skills, including technical report writing and presentation of scientific results
• Demonstrated ability to work effectively in cross-functional teams and manage multiple priorities

What you can expect from us

From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

Equal Opportunity and Inclusion

Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Salary Range

130,384.05USD -176,401.95 USD

About Amgen

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen