Sr. Scientist I (Immunology) - in vitro & in vivo studies

ModeX Therapeutics Inc; Weston (MA); On-site; USD 140,000 - 210,000; Full time

Job summary

ModeX Therapeutics is seeking a Senior Scientist with immunology expertise to advance next-generation immune therapies. You will test novel biologics, delineate mechanisms of action, and address key biological questions within a fast-growing biotech environment.

The role emphasizes independent execution of complex immunoassays, collaboration across project teams, and contribution to internal scientific communications.

Qualifications

• B.S. or M.S. in immunology, immune-oncology or related field.
• Sr. Scientist I: 15+ years of relevant research experience; must have industry experience (10+ years).
• Hands-on expertise in immunology and immunotherapy, with ability to independently evaluate and apply new concepts and immunoassays.

Responsibilities

• Develop biologic immune therapies and test novel candidates.
• Plan and perform in vitro and in vivo studies to characterize drug candidates and mechanisms of action.
• Establish mechanistic insights on targets and immune responses.
• Develop functional assays using primary immune cells (human, mouse, NHP) and establish SOPs.
• Collaborate with cross-functional teams to drive data-driven decisions and program progression.
• Contribute to scientific communications and internal reports.

Skills

Immunology

Immunotherapy

Flow cytometry

ELISA

Luminex assays

In vivo studies

Mouse handling

Data analysis

Mentoring juniors

Education

B.S. or M.S. in immunology or related field

Job description

ModeX Therapeutics is seeking a highly skilled and motivated Senior Scientist with experience in immunology to support the development and progression of new immune therapies. The successful candidate will work with ModeX’s team to test novel biologic drug candidates, delineate their mechanism of action, and address biological questions. This is an exciting opportunity to be part of a cross-functional team and contribute to the development of next-generation therapeutics in a fast-paced, rapidly growing biotech company with a bold vision.

Key Responsibilities

• Play a key role in the development of new biologic drugs for immunotherapy
• Independently propose, plan and perform in vitro and in vivo studies to characterize the company’s drug candidates and their mechanism of action
• Establish mechanistic insights addressing the impact of novel targets on immune responses
• Develop and perform complex functional assays using primary immune cells (human, mouse, NHP)
• Design, develop, troubleshoot and establish in vitro assays and in vivo models and standard operating procedures as needed
• Collaborate cross-functionally with project teams to ensure data-driven decision-making and timely progression of programs.
• Contribute to scientific communications, including internal reports and presentations

Qualifications

• B.S. or M.S. in immunology, immune-oncology or related field
• Sr. Scientist I: 15+ years of relevant research experience; must have industry experience (10+ years)
• Strong, hands-on expertise in immunology and immunotherapy, with the ability to independently evaluate and apply new concepts and immunoassays
• Demonstrate mastery of complex functional assays using primary immune cells, including multi-color flow cytometry, ELISA and Luminex
• Extensive experience with in vivo studies, incl. including mouse handling, multiple dosing routes (IV, IP, SC), tumor models, and tissue collection
• Proven ability to work independently, prioritize effectively, and drive projects forward in a fast-paced biotech environment
• Excellent written and oral communication, organization, and data analysis skills
• Outstanding troubleshooting and problem-solving skills
• Highly collaborative mindset, with the confidence to contribute new ideas and mentor junior team members as needed

ModeX Therapeutics is an Equal Opportunity Employer