Sr. Scientist I (Immunology) - in vitro & in vivo studies

ModeX Therapeutics, Inc.; Weston (MA); On-site; USD 150,000 - 160,000; Full time

Job summary

ModeX Therapeutics is seeking a highly skilled Senior Scientist with immunology experience to advance immune therapies. You will test novel biologics, delineate mechanisms of action, and address key biological questions within a fast-growing biotech setting.

The role involves cross-functional collaboration and mentoring junior team members. The candidate will lead in vitro and in vivo studies, develop functional assays using human/mouse/NHP immune cells, and contribute to scientific

Qualifications

• B.S./M.S. in immunology, immune-oncology or related field.
• 15+ years of relevant research experience; 10+ years in industry.
• Mastery of immunology and immunoassays; independent thinker.

Responsibilities

• Develop biologic drugs for immunotherapy.
• Plan and perform in vitro and in vivo studies to characterize drug candidates and MOA.
• Establish mechanistic insights on targets and immune responses.
• Develop complex functional assays using primary immune cells (humans, mice, NHP).
• Design and implement in vitro assays and in vivo models; SOPs as needed.
• Collaborate with cross-functional teams for data-driven decisions.
• Contribute to internal reports and presentations.

Skills

Immunology

Immunotherapy

In vivo studies

Flow cytometry

ELISA

Luminex

Team leadership

Data analysis

Education

B.S./M.S. in immunology

Job description

#810

Hiring In

WESTON , Massachusetts , United States

Position Type

Full-time (30+ Hours)

Work Schedule

Monday-Friday 9:00am-5:30pm

Company Overview

ModeX Therapeutics, an OPKO Health company, is the leading clinical-stage biopharmaceutical company developing unique and proprietary-multispecific therapeutics. Its MSTAR platform unites the power of multiple biologics in a single molecule to create multispecific antibodies that bind four or more targets with unprecedented versatility and potency for complex diseases. Its promising first-in-class immunology pipeline includes candidates against immune diseases, including cancer (both solid and hematologic tumors), immune impairment, as well as several of the world's most pressing viral threats. Its founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients. ModeX is based in Weston, Massachusetts. For more information, please visit www.modextx.com.

Job Description

ModeX Therapeutics is seeking a highly skilled and motivated Senior Scientist with experience in immunology to support the development and progression of new immune therapies. The successful candidate will work with ModeX’s team to test novel biologic drug candidates, delineate their mechanism of action, and address biological questions. This is an exciting opportunity to be part of a cross-functional team and contribute to the development of next-generation therapeutics in a fast-paced, rapidly growing biotech company with a bold vision.

Key Responsibilities:

• Play a key role in the development of new biologic drugs for immunotherapy
• Independently propose, plan and perform in vitro and in vivo studies to characterize the company’s drug candidates and their mechanism of action
• Establish mechanistic insights addressing the impact of novel targets on immune responses
• Develop and perform complex functional assays using primary immune cells (human, mouse, NHP)
• Design, develop, troubleshoot and establish in vitro assays and in vivo models and standard operating procedures as needed
• Collaborate cross-functionally with project teams to ensure data-driven decision-making and timely progression of programs.
• Contribute to scientific communications, including internal reports and presentations

Qualifications:

• B.S. or M.S. in immunology, immune-oncology or related field
• Sr. Scientist I: 15+ years of relevant research experience; must have industry experience (10+ years)
• Strong, hands-on expertise in immunology and immunotherapy, with the ability to independently evaluate and apply new concepts and immunoassays
• Demonstrate mastery of complex functional assays using primary immune cells, including multi-color flow cytometry, ELISA and Luminex
• Extensive experience with in vivo studies, incl. including mouse handling, multiple dosing routes (IV, IP, SC), tumor models, and tissue collection
• Proven ability to work independently, prioritize effectively, and drive projects forward in a fast-paced biotech environment
• Excellent written and oral communication, organization, and data analysis skills
• Outstanding troubleshooting and problem-solving skills
• Highly collaborative mindset, with the confidence to contribute new ideas and mentor junior team members as needed

ModeX Therapeutics is an Equal Opportunity Employer

Pay Range

The estimated pay range for this job. Disclosing pay information promotes competitive and equitable pay. The actual pay rate will depend on the person's qualifications and experience. $150,000.00 - $160,000.00 / year

Pay Transparency

In order to support the Fair Compensation Strategy by the US Govt., HR Dept., clients are required to adhere to "Pay Transparency Law"; in the impacted states; that have mandated the employers to list the salary ranges in Job advertisements or postings for job opportunities and Job promotions.