Sr. Scientist Bioinformatics, Computational Biology, Proteomics

BioSpace; South San Francisco (CA); On-site; USD 150,000 - 190,000; Full time

Benefits offered by this job

Competitive benefits

Flexible work models

Stock-based incentives

Job summary

Amgen seeks a hands-on Sr. Scientist Bioinformatics in Computational Biology, Proteomics, to develop computational tools and data infrastructure supporting the Discovery Proteomics Group at the South San Francisco campus.

The role combines proteomics expertise with software engineering to enable biomarker discovery, target evaluation, and mechanism‑of‑action studies. A PhD or equivalent with strong coding and data analysis skills is required.

Qualifications

• Doctorate degree required.
• Master's degree with 3+ years scientific experience or Bachelor's with 5+ years experience.
• Fluency in Python, R, and SQL; experience with data processing and visualization.

Responsibilities

• Develop computational tools and data infrastructure for proteomics in Discovery Proteomics.
• Perform statistical analysis, data ingestion, and pipeline implementation for proteomics data.
• Collaborate with cross-functional teams and present analysis results to stakeholders.

Skills

Python

R

SQL

Unix/Linux

AWS

Docker

Machine learning

Data visualization

Statistical analysis

Proteomics

Education

Doctorate degree

Master's degree

Bachelor's degree

Tools

Unix/Linux tooling

Cloud computing (AWS)

Version control (Git)

Job description

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared mission to serve patients living with serious illnesses drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr. Scientist Bioinformatics, Computational Biology, Proteomics

Lets do this. Letschange the world.

What You Will Do

Amgen is seeking a hands‑on bioinformatician to develop computational tools and data infrastructure to support the Discovery Proteomics Group. The successful candidate will combine strong scientific expertise in proteomics, bioinformatics, and drug discovery with software engineering skills to understand experimental and discovery needs and translate them into fit‑for‑purpose computational solutions. In this vital role, they will conduct statistical analysis, data ingestion, database and tool development, and computational pipeline implementation for proteomics data to support biomarker discovery, target evaluation, experimental design, and mechanism‑of‑action studies. The successful candidate will join the Discovery Proteomics group at our South San Francisco campus.

Key Responsibilities

This role will enable Amgen’s preclinical pipeline through the delivery of innovative technologies and technical expertise. Responsibilities will include the development and implementation of data analysis, management, and visualization strategies for complex datasets generated by mass spectrometry and other technologies. The successful candidate will be expected to work closely with scientists from different functions and therapeutic areas, deliver and present analysis results to key stakeholders, collaborate across both genomic and proteomic platforms for data integration and mining, and utilize available external resources where appropriate.

What We Expect Of You

We are all different, yet we all use our unique contributions to serve patients. The Sr. Scientist Bioinformatics, Computational Biology, Proteomics we seek is a scientifically driven, collaborative, and innovative expert.

Basic Qualifications

Doctorate degree

OR

Masters degree and 3 years of scientific experience

OR

Bachelors degree and 5 years of scientific experience

Preferred Qualifications

• PhD in Computational Biology, Bioinformatics, Statistics, Proteomics, or Biology.
• Expertise in large-scale quantitative proteomics and other omics data analysis.
• Fluency in Python, R, and SQL, and familiarity with analytic techniques/packages necessary for statistical analysis, data processing, data ingestion, data visualization, and basic machine learning approaches. Familiarity with deep learning packages is a plus.
• Working knowledge of Unix/Linux and cloud computing (AWS) environments.
• Experience in version control, Docker containers, and other best practices for coding project management, reproducible data analysis, and documentation.
• Experience in meta-analysis with publicly available large proteomics studies (e.g., GTEx, CPTAC) is a plus.
• Strong background in biology or chemistry, especially as it pertains to human diseases in the fields of Immunology, Oncology, Inflammation, and Cardiometabolic Disease.
• Proven track record of independent critical thinking and scientific achievement.
• Strong verbal and written skills, and an ability to work independently as well as in small teams. Willingness and ability to collaborate effectively across different scientific disciplines and with colleagues in cross‑functional teams.

What You Can Expect Of Us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the Base Salary, Amgen offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time‑off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Application Deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Internal Only Posting (or Pre‑ID Candidate)

Amgen anticipates accepting applications until 1 week before the posting; however, we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

In any materials you submit, you may redact or remove age‑identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.