SR. RESEARCH ASSOCIATE/ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT

Initial Therapeutics, Inc.; Redwood City (CA); On-site; USD 108,000 - 150,000; Full time

Benefits offered by this job

Annual bonus

Equity

ESPP

401(k) with Roth

Health plans

FSA/HSA

Paid time off

Job summary

Adicet Bio, Inc. is seeking a Research Associate/Associate Scientist in Nonclinical Development to coordinate in vivo and ex vivo studies evaluating immune-cell and gene-therapy platforms. You will design experiments, plan timelines, and work with CROs to ensure aligned endpoints and robust data.

Ideal candidates have immuno-oncology experience, strong technical skills in flow cytometry, qPCR/ddPCR, ELISA, and in vivo imaging, and excellent organizational and communication abilities.

Qualifications

• Bachelor’s degree with 5+ years R&D, or Master’s with 3+ years, in immuno-oncology preferred.
• Experience designing and interpreting in vivo studies using murine xenograft or humanized models.
• Proficiency administering therapeutic agents and creating xenograft models via IV, IP, and subcutaneous routes.
• Strong blood collection skills and tissue processing for flow cytometry.
• Experience with aseptic mammalian cell culture for nonclinical in vivo studies.
• Experience with in vivo bioluminescence/fluorescence imaging (IVIS).
• Experience with flow cytometry, ELISA, qPCR/ddPCR, cytokine bead assays preferred.
• Excellent organization, communication, data analysis, and documentation.
• Ability to work independently and manage multiple priorities.

Responsibilities

• Coordinate and execute in vivo and ex vivo nonclinical studies evaluating immune-cell and gene-therapy platforms.
• Contribute to study design, timelines, and data-driven decisions to advance programs.
• Collaborate with cross-functional teams and CROs to coordinate study execution and endpoints.
• Perform necropsies and process tissues for analyses (flow cytometry, qPCR/ddPCR, ELISA).
• Maintain accurate, complete experimental records in line with quality standards.

Skills

Immuno-oncology

Data analysis

Independent work

Project coordination

Communication

Troubleshooting

Education

Bachelor’s degree in biological sciences or related field

Master’s degree in biological sciences

Tools

Flow cytometry

qPCR/ddPCR

ELISA

In vivo imaging (IVIS)

Aseptic mammalian cell culture

Xenograft model establishment

Job description

JOIN US!

Adicet Bio, Inc. is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CARs), to facilitate durable activity in patients. For more information, please visit our website at https://www.adicetbio.com.

RESEARCH ASSOCIATE/ ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT

Key responsibilities:

• Coordinate and execute in vivo and ex vivo nonclinical studies to evaluate Adicet’s immune-cell and gene-therapy platforms, including efficacy, pharmacokinetic/pharmacodynamic, and safety assessments in relevant murine oncology and immunology models.
• Contribute to study design, experimental planning, timeline development, and data-driven decision‑making to support program advancement.
• Collaborate and communicate effectively with cross‑functional teams and external contract research organizations to coordinate study execution, troubleshoot technical challenges, and ensure study endpoints align with program objectives.
• Perform necropsies and process tissues for downstream analyses, including flow cytometry, qPCR/ddPCR, and ELISA, to characterize pharmacologic activity and elucidate mechanisms of action.
• Maintain accurate, complete, and well‑organized experimental records in accordance with internal documentation and quality standards.

Qualifications:

• Bachelor’s degree in biological sciences or a related field with 5+ years of relevant R&D experience, or a Master’s degree with 3+ years of experience, preferably in immuno‑oncology, within an industry setting.
• Significant experience designing, executing, analyzing, and interpreting in vivo studies using murine xenograft disease models and/or humanized immunology models.
• Demonstrated proficiency administering therapeutic agents and establishing xenograft models through intravenous, intraperitoneal, and subcutaneous routes in mice.
• Strong technical proficiency in blood collection, including submandibular and tail‑vein sampling, as well as tissue necropsy and sample processing for flow‑cytometry applications.
• Experience with aseptic mammalian cell culture, including the maintenance and preparation of human cancer cell lines for nonclinical in vivo studies.
• Hands‑on experience with in vivo bioluminescence and/or fluorescence imaging, including image acquisition and data analysis using IVIS platforms.
• Experience with laboratory techniques such as flow cytometry, ELISA, qPCR/ddPCR, and cytokine bead‑based assays is preferred.
• Excellent organizational, communication, data‑analysis, and technical‑documentation skills.
• Demonstrated ability to work independently, troubleshoot scientific and technical challenges, and contribute innovative solutions.
• Ability to manage multiple priorities and thrive in a fast‑paced, collaborative, and supportive research environment.

Pay Range

$108,000 - $150,000 USD

Required Work Location

Employees are required to be onsite at least three days per week (Tuesday–Thursday mandatory). Some roles may require full‑time onsite presence.

Benefits

• Competitive base salary, annual cash bonus, long‑term incentives (equity), Employee Stock Purchase Plan (ESPP), and a 401(k) with ROTH and a 4.5% company match.
• Comprehensive health plans (medical, dental, vision, etc.), Flexible Health and Commuter Spending Accounts (FSA) and a company‑matched Health Savings Account (HSA).
• Life, AD&D, short and long‑term disability insurance, and legal, pet, and various voluntary insurance programs.
• Generous paid time‑off including 13 company holidays, paid end‑of‑year winter break, vacation, sick time, and paid parental leave.

About the Company

Adicet Bio, Inc. is a clinical stage biotechnology company focused on discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer.

Adicet is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.