SR. RESEARCH ASSOCIATE/ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT

Adicet Bio, Inc; Redwood City (CA); On-site; USD 108,000 - 150,000; Full time

Benefits offered by this job

Health plans

401(k) with company match

Employee Stock Purchase Plan (ESPP)

Generous PTO & holidays

Job summary

Adicet Bio, Inc. is a clinical stage biotech company focused on allogeneic gamma-delta T cell therapies for autoimmune diseases and cancer.

The Research Associate/Associate Scientist, Nonclinical Development, will coordinate and execute in vivo and ex vivo studies to evaluate immune-cell platforms, contribute to study design, and collaborate with CROs to ensure endpoints align with program goals. The role requires 3–5+ years of experience with in vivo models, aseptic mammalian culture, and

Qualifications

• Degree in biological sciences with required years of R&D experience in immuno-oncology or related field.
• Experience designing and executing in vivo/nonclinical studies with xenograft or humanized models.
• Strong data analysis, documentation, and independent problem solving.
• Proficiency with flow cytometry, ELISA, qPCR/ddPCR, and IVIS imaging.
• Excellent organizational and communication skills, ability to work in a fast-paced team.

Responsibilities

• Coordinate and execute in vivo/ex vivo nonclinical studies to evaluate platforms.
• Contribute to study design, planning, timelines, and data-driven decisions.
• Collaborate with cross-functional teams and CROs to align study endpoints.
• Perform necropsies and tissue processing for flow cytometry and assays.
• Maintain accurate experimental records per quality standards.

Skills

Data analysis

Independent work

Communication

Technical documentation

Team collaboration

Education

Bachelor’s degree in biological sciences or related field

5+ years R&D experience or Master’s +3 years

Tools

Flow cytometry

qPCR/ddPCR

ELISA

IVIS imaging

Tissue necropsy

Job description

Adicet Bio, Inc. is a clinical stage biotechnology company discovering and developing allogeneic gamma‑delta T cell therapies for autoimmune diseases and cancer. Adicet is advancing a pipeline of “off‑the‑shelf” gamma‑delta T cells, engineered with chimeric antigen receptors (CARs), to facilitate durable activity in patients. For more information, please visit our website at https://www.adicetbio.com.

RESEARCH ASSOCIATE/ASSOCIATE SCIENTIST, NONCLINICAL DEVELOPMENT

Key Responsibilities

• Coordinate and execute in vivo and ex vivo nonclinical studies to evaluate Adicet’s immune‑cell and gene‑therapy platforms, including efficacy, pharmacokinetic/pharmacodynamic, and safety assessments in relevant murine oncology and immunology models.
• Contribute to study design, experimental planning, timeline development, and data‑driven decision‑making to support program advancement.
• Collaborate and communicate effectively with cross‑functional teams and external contract research organizations to coordinate study execution, troubleshoot technical challenges, and ensure study endpoints align with program objectives.
• Perform necropsies and process tissues for downstream analyses, including flow cytometry, qPCR/ddPCR, and ELISA, to characterize pharmacologic activity and elucidate mechanisms of action.
• Maintain accurate, complete, and well‑organized experimental records in accordance with internal documentation and quality standards.

Qualifications

• Bachelor’s degree in biological sciences or a related field with 5+ years of relevant R&D experience, or a Master’s degree with 3+ years of experience, preferably in immuno‑oncology, within an industry setting.
• Significant experience designing, executing, analyzing, and interpreting in vivo studies using murine xenograft disease models and/or humanized immunology models.
• Demonstrated proficiency administering therapeutic agents and establishing xenograft models through intravenous, intraperitoneal, and subcutaneous routes in mice.
• Strong technical proficiency in blood collection, including submandibular and tail‑vein sampling, as well as tissue necropsy and sample processing for flow‑cytometry applications.
• Experience with aseptic mammalian cell culture, including the maintenance and preparation of human cancer cell lines for nonclinical in vivo studies.
• Hands‑on experience with in vivo bioluminescence and/or fluorescence imaging, including image acquisition and data analysis using IVIS platforms.
• Experience with laboratory techniques such as flow cytometry, ELISA, qPCR/ddPCR, and cytokine bead‑based assays is preferred.
• Excellent organizational, communication, data‑analysis, and technical‑documentation skills.
• Demonstrated ability to work independently, troubleshoot scientific and technical challenges, and contribute innovative solutions.
• Ability to manage multiple priorities and thrive in a fast‑paced, collaborative, and supportive research environment.

Employees are required to be onsite at least three days per week (Tuesday–Thursday mandatory). Some roles require full‑time onsite presence.

Pay Range: $108,000—$150,000 USD

We offer a competitive compensation package including base salary, annual cash bonus, long‑term incentives (equity), Employee Stock Purchase Plan (ESPP) and a 401(k) with ROTH and a 4.5% Company match.

We also offer comprehensive health plans (medical, dental, vision, etc.), Flexible Health and Commuter Spending Accounts (FSA), a matched Health Savings Account (HSA), life, AD&D, short and long‑term disability insurance, and legal, pet, and other voluntary insurance programs.

Generous paid time‑off is available, including 13 company holidays, paid end‑of‑year winter break, vacation, sick time, and paid parental leave.

Adicet is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.