Sr. Research Associate 1

BioSpace; Novato (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

BioSpace is seeking a passionate Sr. Research Associate 1 to support manufacturing processes. This role involves lab-based purification work, collaborating with scientists, and improving production efficiency. Candidates should have extensive experience in purification techniques and strong communication skills, with opportunities for growth in a dynamic environment.

Qualifications

• 6+ years experience in process development or manufacturing sciences.
• 4+ years experience with M.S. degree.
• Experience with lab scale purifications is preferred.

Responsibilities

• Assist in the design and execution of studies for process improvements.
• Operate bench scale filtration and chromatography systems.
• Document experimental data and support data analysis.

Skills

Purification experience on ÄKTA system

Analytical assays knowledge

Troubleshooting of purification processes

Strong communication skills

Organizational skills

Education

B.S. in Chemical/Biochemical/Biomedical Engineering

M.S. in Chemical/Biochemical/Biomedical Engineering

Tools

MS Office

Statistical software (e.g., JMP)

Job description

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BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients’ lives.

SENIOR RESEARCH ASSOCIATE, NOVATO TECHNICAL SUPPORT SUMMARY Novato Technical Support (NTS) at BioMarin is the technical partner for commercial and clinical operations and actively supports manufacturing processes throughout the product lifecycle. We are an inclusive, high-performing, highly motivated, and collaborative group looking for an innovative and passionate individual with strong purification skills and familiarity with large scale purification operations to become an integral part of our downstream team. You will join a team of scientists and research associates working to resolve manufacturing challenges, evaluate new technologies, support technology transfers, and facilitate continuous process improvement to ensure robustness for our biologics production processes. Applicants who have experience with lab scale purifications are preferred. The majority of the work will be lab based, involving process development, characterization, and optimization, along with some execution of analytical methods. The individual will develop experimental studies to troubleshoot and better understand BioMarin’s manufacturing purification processes. This individual must have strong communication skills, as they will be involved in projects that involve presenting data to collaborators and will assist in writing memos, protocols and reports. The ideal candidate is a self-starter, who focuses on transparent and honest communication, is dependable, cares intensely about helping others, and is comfortable making decisions while dealing with uncertainty. RESPONSIBILITIES

• You will assist in the design and execution of studies to enable continuous process improvements of BioMarin's manufacturing purification processes.
• Working with other scientists in the team, you will operate bench scale filtration, chromatography (on ÄKTA systems) and tangential flow filtration for routine commercial manufacturing support.
• You will perform analytical assays (HPLC, SDS-PAGE, western blot, microtiter plate assays) related to experimental studies.
• You will support investigations that help us understand and resolve complex manufacturing issues and assess their potential impact to product quality.
• You will evaluate raw materials for use in commercial manufacturing processes.
• You will have opportunities to evaluate novel technologies that will support current and future manufacturing processes.
• As a researcher, you will document experimental data, interpret results and support data analysis. You will also assist in writing memorandums, protocols and reports.
• You will contribute to safety, 6S and sustainability efforts in the lab.
  
  
  

REQUIRED SKILLS

• Bench scale purification experience on ÄKTA system (including column packing and chromatography).
• Knowledge of analytical assays (HPLC, SDS-PAGE, western blot, microtiter plate assays) is a plus.
• Experience with troubleshooting of purification processes.
• Accurate documentation of experimental work, data analysis and results.
• Demonstrated record of strong communication skills (oral and written).
• Proficient with MS Office, Excel, PowerPoint.
• Experience with statistical software (e.g., JMP) is a plus.
• Must be willing to work on multiple projects.
• A strong team player with good collaborative and people skills.
• Strong organization and prioritization skill, with attention to details and ability for in-depth research and analysis.
• Highly motivated with the ability to resolve technical issues, develop and implement corrective solutions, be able to quickly adapt and respond effectively to changes.
  
  
  

EDUCATION

• B.S. degree in Chemical/Biochemical/Biomedical Engineering or related disciplines with 6+ years experience in process development or manufacturing sciences.
• M.S. degree in Chemical/Biochemical/Biomedical Engineering or related disciplines with 4+ years of experience.
  
  
  

WORK ENVIRONMENT / PHYSICAL DEMANDS

• This role is primarily onsite (5 days a week, 8-hour days) with occasional evening or weekend work required.
• This role is primarily a laboratory position; contact with chemicals is part of the job. The employee will be trained to use common lab equipment and minimize exposure to hazards. Desktop or laptop computer work is also a major component of the job.
• The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
• While performing the duties of this job, the employee is occasionally exposed to work near moving mechanical parts; fumes or airborne particles; toxic or caustic chemicals; risk of electrical shock and vibration. The noise level in the work environment is usually moderate.
• The employee may frequently be required to sit and talk or hear. The employee is occasionally required to stand; walk; use hands to handle or feel; reach with hands and arms; climb or balance; stoop, knee crouch, or crawl. The employee must occasionally lift and/or move up to 25 pounds.
  
  
  

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Internet News

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