Sr. Principal Scientist (Sr. Research Scientist)

ICON; Lenexa (KS); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Health insurance

Retirement planning

LifeWorks EAP program

Paid time off

Job summary

ICON in Lenexa, KS seeks a Sr. Principal Scientist to design, conduct, and analyze complex clinical research studies. You will lead method development for ligand binding assays, mentor junior staff, and collaborate with cross-functional teams to ensure timely execution of trials.

The candidate will contribute scientifically, engage with sponsors on assay requirements, and help advance new treatments with high-quality data and publications.

Qualifications

• PhD with CRO experience or MS/BS with extensive lab background.
• Expertise in ligand binding assays and method development.
• Publication record or presenter in regulated field preferred.

Responsibilities

• Design and execute experiments for LBA method development.
• Mentor junior scientists and advise operations on methods.
• Communicate project status to internal teams and clients.
• Provide scientific input for technology investments and new projects.

Skills

LBA method development

ELISA & ECLIA

Data analysis

Scientific communication

Mentoring

Cross-functional collaboration

Education

PhD in Life Sciences

MS/BS with 10+ years lab experience

Tools

SoftMax Pro

Watson

Job description

Senior Research Scientist - US, Lenexa, KS Office-based- Full-Time

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

We are excited to be seeking a new Sr. Principal Scientist (Sr. Research Scientist) at ICON in Lenexa, Kansas (KS). The Sr. Principal Scientist (Sr. Research Scientist) will play a crucial role in designing, conducting, and analyzing complex clinical research studies.

You will leverage your expertise to drive innovative research initiatives, develop scientific protocols, and collaborate across departments to ensure the successful execution of clinical trials that advance new treatments and therapies.

A successful candidate will have advanced experience in ligand binding assays:

• ELISA, ECLIA
• PK, PD, and immunogenicity
• Usage of relevant software (e.g. SoftMax Pro, Watson)
• Neutralizing antibody (NAb)

What you'll be doing:

Method Development

• Independently designs and executes experiments for LBA method development.
• Develops new scientific approaches to method development and communicates these to the global science team.
• Mentor more junior scientists and advise operation on developed methods.
• Responsible for organized and effective communication with the internal team and management, and with clients regarding project status, scheduling, barriers, etc.

Scientific

• Provide scientific input to management and BD about new technology investments and lines of service.
• Drive new business by consulting with sponsors on assay requirements for new projects.
• Promotes ICON utilizing scientific skills through scientific communication such as external publication of posters and journal articles.
• Mentor and train staff on scientific topics.

Quality and Timely Work Execution

• Takes initiative in process development and SOP/WI writing.
• Has a thorough understanding and complies with GLP and other appropriate regulations.
• Develops rugged and economical assays.
• Performs data review of other scientist's work.

Sample Analysis and Assay Validation

• Provides key assay input to the validation and bioanalysis team(s) to ensure successful execution.
• Provide support to Laboratory Operations staff regarding assay quality, expected results, troubleshooting and data review.
• May perform and document maintenance, trouble-shooting and repairs on advanced instrumentation with support of service engineers or other trained supervisory personnel.

Your Profile:

• PhD with applicable research in a relevant scientific field and 2+ years of CRO experience
• OR MS or BS in Science and 10+ years of experience in a relevant laboratory environment
• Extensive experience in clinical research design, data analysis, and interpretation, with a strong publication record.
• Presenter/Publisher in Regulated relevant field preferred.
• Strong analytical and problem-solving skills, with a commitment to scientific excellence.
• Excellent communication and leadership skills, with the ability to work effectively in cross-functional teams.

#LI-KM3

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here