Sr. Director - Global OSD, Technical Operations, Science & Innovation

AstraZeneca; Newark (DE); Hybrid; USD 210,000 - 314,000; Full time

Job summary

AstraZeneca in Newark, US, is seeking a Senior Director Global OSD to lead the technical organisation responsible for on-market OSD portfolio performance. Based in Newark with frequent office presence at Mt.

Vernon, the role drives manufacturing excellence, science and Lean principles across the product lifecycle. You will develop strategy with Manufacturing Technology and Product Development, manage budgets and headcount, and embed AI and digital analytics to improve reliability, compliance,

Qualifications

Responsibilities

• Lead and develop a diverse technical organisation delivering product and process performance for AstraZeneca’s commercial OSD portfolio.
• Coach direct reports and foster a culture of continuous improvement and innovation.
• Shape regional strategy as part of the North Americas Commercial Operations Leadership Team.
• Use data, AI and advanced analytics to generate insights and drive performance improvements.
• Maintain a best-in-class technical support model for internal sites and external partners.
• Manage the team budget, headcount and revenue; ensure resources are deployed effectively.
• Demonstrate understanding of drug development and lifecycle management, and lead investments within a complex operational environment.

Skills

Leadership

Data analytics

AI

Lean operations

Budget management

Cross-functional collaboration

Communication skills

Job description

Location: Newark, US ( with frequent office presence in Mt. Vernon)

Hybrid working model: 3 days per week in the office location

Introduction to role:

Are you ready to lead a team that makes a difference in the pharmaceutical industry? This senior leadership role provides strategic and operational direction for the global organisation responsible for on-market technical support to AstraZeneca’s commercial Oral Solid Dosage (OSD) portfolio.

Based in Newark, US, with frequent office presence in Mt. Vernon. The position leads a high-performing team that supports OSD platform teams and senior scientific experts, ensuring robust, reliable and innovative manufacturing performance across the product lifecycle.

How will you shape the future of OSD manufacturing, harnessing science, digital tools and Lean ways of working to deliver medicines that truly matter?

Accountabilities

• In this role, the Senior Director Global OSD leads and develops a diverse technical organisation focused on delivering strong product and process performance for AstraZeneca’s commercial OSD portfolio.
• The position manages and coaches direct reports, building capability, engagement and succession while fostering a culture of continuous improvement and innovation.
• As a key member of the North Americas Commercial Operations Leadership Team, the role shapes regional strategy, aligns cross-functional priorities and translates strategy into clear, actionable plans that drive value across the network.
• The Senior Director is accountable for proactively managing product and process robustness, using data, AI and advanced analytics to generate insights and drive performance improvements. The role develops and implements science and innovation strategies for OSD manufacturing, with particular emphasis on material science, pharmaceutics and new technology introduction in partnership with Manufacturing Technology and Product Development.
• A critical part of the remit is to maintain a best-in-class technical support model for internal manufacturing sites and external partners, ensuring outstanding customer service and effective risk management. The Senior Director sets clear direction, communicates with impact and influences at all levels to embed Lean principles, operational excellence and compliant ways of working across the function.
• The role also carries financial accountability for the team’s budget, including headcount and revenue, ensuring resources are deployed effectively to deliver strategic priorities. Operating confidently in a global environment, the Senior Director builds an organisation ready for future challenges and change, contributing significantly to the success of Operations and the commercial viability and availability of current products.
• Have an excellent understanding of the overall drug development and commercialization process from development, launch and through life cycle management
• Extensive pharmaceutical proven experience specifically in relation to Oral Solid Dosage (OSD) form drug products.
• Have a broad understanding of the various scientific subject areas that they have accountability for with expert knowledge of Oral Solid Dosage form manufacturing technology.
• Have a detailed understanding of principles, applications and management of SHE, cGMP and Lean.
• Experience in Operations and/or R&D with a track record of successful project leadership and delivery within a matrix organization and lean leadership.
• Evidence of excellent communication skills and build excellent relationships with customers/key partners.
• Proven experience leading large, multi-site or global technical organisations within commercial manufacturing
• Demonstrated success in deploying AI, digital or advanced analytics solutions to improve manufacturing performance
• Strong background in material science or pharmaceutics applied to OSD development or commercialisation
• Experience introducing new technologies or platform capabilities into commercial operations at scale
• Track record of building high-performing, inclusive teams and developing senior technical leaders
• Demonstrable experience overseeing substantial budgets and leading investment decisions within a complex operational environment. An understanding of capital planning and the budgeting lifecycle - encompassing forecasting, prioritisation, approval governance, and performance tracking - would be highly advantageous.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers the chance to work at the intersection of pioneering science, digital innovation and Lean operations, where complex challenges are tackled with rigor, curiosity and collaboration. Here, ideas move quickly from concept to reality; investment in technology, skills and development opens up varied global career paths; and work on medicines that address unmet needs brings a strong sense of purpose. Colleagues support one another across generations and backgrounds, sharing knowledge, challenging assumptions and constantly learning as they help transform molecules into medicines for patients worldwide.

The annual base pay for this position ranges from $209,559.20 - $314,338.80 Annual USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.