Sr. Bioinformatics Scientist – Cell Free DNA Technology Development

Personalis, Inc.; Fremont (CA); On-site; USD 150,000 - 190,000; Full time

Job summary

A leading company specializing in cancer management is hiring a Sr. Bioinformatics Scientist to innovate in cell-free DNA technology development. The role offers an opportunity to work collaboratively with expert teams in advancing genomic profiling and therapeutic strategies. Key responsibilities include designing and optimizing bioinformatics products, analyzing complex datasets, and contributing to a new wave of precision medicine. Competitive compensation and benefits package included.

Benefits

Annual performance-based bonus

401(k) match

Tuition reimbursement

Onsite gym

Qualifications

• Ph.D. required with extensive cancer genomics experience.
• Proficient in programming languages (Python, R).
• Experience in liquid biopsy analysis.

Responsibilities

• Design and develop bioinformatics products for cancer genomics.
• Model and analyze complex genomic datasets.
• Communicate findings through publications and presentations.

Skills

Cancer genomics

Somatic mutational detection

Programming (Python, R)

Data analysis

Education

Ph.D. in bioinformatics, genomics, or related field

Job description

Sr. Bioinformatics Scientist – Cell Free DNA Technology Development

Join to apply for the Sr. Bioinformatics Scientist – Cell Free DNA Technology Development role at Personalis, Inc.

Sr. Bioinformatics Scientist – Cell Free DNA Technology Development

Join to apply for the Sr. Bioinformatics Scientist – Cell Free DNA Technology Development role at Personalis, Inc.

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At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

The Bioinformatics Senior Scientist will work with a world-class, dynamic team of bioinformatics scientists, software engineers, and laboratory scientists, developing, testing, and applying cutting-edge cell-free and solid tumor cancer genomics products. Further, the Bioinformatics Scientist will be working alongside our clinical evidence generation teams, applying our cell-free solutions to large cancer patient cohorts and profiling patient response to therapy with our cfDNA platforms. This position will directly contribute to a new generation of genomics-based precision-medicine products for profiling MRD, ctDNA dynamics, and patient response to treatment. Our products are used by pharma, biotech, hospitals, and clinicians for managing patient treatment and therapeutic selection.

Days onsite: Monday and Tuesday

Responsibilities:

• Design, develop, and build upon our novel cell-free platforms and products, including our NeXT Personal MRD liquid biopsy platform
• Work cross-functionally to translate collaborative findings into actively developed cutting-edge products
• Design and execute scientific projects and experiments focused on product feature feasibility, demonstrating feature performance, and clinical advantages of our cell-free platforms
• Modeling and analysis of large, complex genomics datasets using novel methods to generate biological insights
• Work with scientific teams to translate scientific findings into actively developed groundbreaking products
• Publish results and present at conferences in exciting areas, including cell-free DNA and cancer genomics
  
  

Requirements:

• Advanced degree (Ph.D.) in bioinformatics, genomics, or a related field
• Extensive experience with cancer genomics
• Extensive experience with somatic mutational detection and filtering
• Experience with cancer liquid biopsy analysis
• Proficiency with at least one common programming language (e.g., Python, R)
• A track record of designing and implementing experimental approaches to confirm and elaborate upon findings from complex projects
• Experience in publishing and presenting scientific results
  
  

The hiring range for this position is $150,000 to $190,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Science, and Health Care Provider

• Industries

  Medical Equipment Manufacturing, Pharmaceutical Manufacturing, and Biotechnology Research

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