Sr. Bioinformatics Scientist - Cell Free DNA Technology Development

Davita Inc.; Fremont (CA); On-site; USD 150,000 - 190,000; Full time

Job summary

A leading biotechnology company seeks a Bioinformatics Senior Scientist to innovate in the field of cancer management through cutting-edge genomic solutions. The successful candidate will engage in product development, working with cross-functional teams to advance personalized medicine and contribute to groundbreaking cancer research.

Benefits

Annual performance-based bonus

Medical, dental, and vision benefits

401(k) match and ESPP

Tuition reimbursement

Onsite gym and wellness benefits

Qualifications

• Extensive experience with cancer genomics.
• Proficiency in at least one programming language (Python or R).
• Track record of publication and presentation in scientific research.

Responsibilities

• Design and build products for cell-free cancer genomics.
• Model and analyze large genomics datasets.
• Collaborate to translate findings into developed products.

Skills

Cancer genomics

Somatic mutational detection

Liquid biopsy analysis

Programming (Python, R)

Education

Ph.D. in bioinformatics, genomics, or related field

Job description

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

The Bioinformatics Senior Scientist will work with a world-class, dynamic team of bioinformatics scientists,software engineers, and laboratory scientists, developing, testing, and applying cutting-edge cell-free andsolid tumor cancer genomics products. Further, the Bioinformatics Scientist will be working alongside ourclinical evidence generation teams, applying our cell-free solutions to large cancer patient cohorts andprofiling patient response to therapy with our cfDNA platforms. This position will directly contribute to anew generation of genomics-based precision-medicine products for profiling MRD, ctDNA dynamics, andpatient response to treatment. Our products are used by pharma, biotech, hospitals, and clinicians formanaging patient treatment and therapeutic selection.

Days onsite: Monday and Tuesday

Responsibilities:

• Design, develop, and build upon our novel cell-free platforms and products, including our NeXTPersonal MRD liquid biopsy platform


• Work cross-functionally to translate collaborative findings into actively developed cutting-edge products


• Design and execute scientific projects and experiments focused on product feature feasibility, demonstrating feature performance, and clinical advantages of our cell-free platforms


• Modeling and analysis of large, complex genomics datasets using novel methods to generate biological insights
  


• Work with scientific teams to translate scientific findings into actively developed groundbreaking products
  


• Publish results and present at conferences in exciting areas, including cell-free DNA and cancer genomics

Requirements:

• Advanced degree (Ph.D.) in bioinformatics, genomics, or a related field


• Extensive experience with cancer genomics


• Extensive experience with somatic mutational detection and filtering


• Experience with cancer liquid biopsy analysis


• Proficiency with at least one common programming language (e.g., Python, R)


• A track record of designing and implementing experimental approaches to confirm and elaborate upon findings from complex projects


• Experience in publishing and presenting scientific results

The hiring range for this position is $150,000 to $190,000 peryear, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical,dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

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