Sr Associate Scientist, Biology

Scorpion Therapeutics; California (MO); On-site; USD 85,000 - 120,000; Full time

Job summary

Scorpion Therapeutics is seeking a Senior Associate Scientist in Research Oncology to advance immuno-oncology programs and develop cancer therapies. The role emphasizes in vitro assays and mechanism-of-action studies.

The candidate will perform cell culture, gene editing, and primary immune cell isolation, and collaborate with in vivo pharmacology teams to support preclinical mouse models. A strong immunology background is required.

Qualifications

• BS with 5+ years or MS with 3+ years in Immunology, Biology, or related fields.
• Strong expertise in immunology, cell culture, flow cytometry, and assay development.
• Experience with primary immune cells, reporter, cytotoxicity, and cell engineering assays.
• Familiarity with in vivo pharmacology preferred.

Responsibilities

• Develop and execute in vitro cell-based assays using primary and engineered mammalian cells for target validation and candidate characterization.
• Perform mammalian cell culture, gene editing, and primary immune cell isolation.
• Conduct functional assays such as reporter, proliferation, and cytotoxicity tests.
• Collaborate across disciplines and support in vivo pharmacology studies, including preclinical mouse models.

Skills

Immunology

Cell culture

Flow cytometry

Assay development

Primary immune cells

Reporter assays

Cytotoxicity assays

Cell engineering

Education

BS with 5+ years or MS with 3+ years in Immunology/Biology

Job description

Senior Associate Scientist in Research Oncology

Focused on discovering and developing novel cancer therapies with an emphasis on immuno-oncology and engager molecules.

• develop and execute in vitro cell-based assays using primary and engineered mammalian cells for target validation, mechanism-of-action, and candidate characterization
• perform mammalian cell culture, gene editing, and primary immune cell isolation
• conduct functional assays such as reporter, proliferation, and cytotoxicity tests
• collaborate across disciplines and support in vivo pharmacology studies, including preclinical mouse models

Requirements

• BS with 5+ years or MS with 3+ years industry experience in Immunology, Biology, or related fields
• strong expertise in immunology, cell culture, flow cytometry, and assay development
• experience with primary immune cells, reporter, cytotoxicity, and cell engineering assays
• familiarity with in vivo pharmacology preferred

High Value

oncology, immuno-oncology, cell-based assay development, target validation, translational research, preclinical mouse models, assay automation, cross-functional collaboration.

Work Setup

not specified; likely research lab environment.