Specialist IS Business Systems Analyst

Amgen; Holly Springs (NC); On-site; USD 90,000 - 120,000; Full time

Job summary

Amgen is seeking a Specialist IS Business Systems Analyst to drive digital and AI-enabled transformation by aligning business needs with technology solutions.

You will lead cross-functional initiatives across departments, elicit requirements, define scope, manage delivery, ensure compliance, and enable data-driven decision making.

Responsibilities

• Lead medium-to-large digital, automation, data, analytics, and AI-enabled initiatives across multiple departments or functional areas from business need through implementation and adoption.
• Partner with Manufacturing, Business, Technology/IS, Engineering, Automation, Quality, Data, and vendor stakeholders to identify business needs, process improvements, and scalable technology solutions.
• Lead requirements elicitation and process analysis, translating business needs into system requirements, user stories, process flows, acceptance criteria, and measurable success criteria.
• Define and manage project scope, delivery plans, timelines, resources, budgets, risks, dependencies, milestones, and deliverables.
• Manage cross-functional teams through solution design, development, testing, implementation, release readiness, adoption, and post-implementation assessment.
• Support the computerized system/application lifecycle, including implementation, validation/qualification, change control, sustainment, enhancements, integrations, upgrades, periodic reviews, and retirement.
• Identify opportunities to simplify, standardize, and automate business processes, eliminate manual activities, improve data quality, and replace inefficient or legacy workflows.
• Partner with the business to identify, standardize, and operationalize data sources, metrics, KPIs, dashboards, and analytics solutions supporting operational excellence and data-driven decision-making.
• Drive delivery and adoption of digital platforms, workflow automation, dashboards, analytics, and AI-enabled capabilities that improve productivity, quality, decision-making, and user experience.
• Identify appropriate AI/ML and Generative AI use cases, support responsible AI adoption, and contribute to practical guidance and guardrails for AI platforms, tools, and applications.
• Ensure technology solutions comply with applicable Technology, cybersecurity, GxP, data integrity, quality, legal, policy, and operational requirements.
• Communicate project status, risks, decisions, technical approaches, dependencies, and business value to

Job description

Join Amgen's Mission of Serving Patients

At Amgen, if you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Specialist IS Business Systems Analyst

What You Will Do

Let’s do this. Let’s change the world! In this vital role, you will help drive Amgen’s digital and AI-enabled transformation by connecting business needs with practical technology solutions. You will apply business insight, technical judgment, and execution discipline to guide initiatives that improve how teams work, make decisions, and deliver value. This role will also evaluate opportunities thoughtfully, align the right stakeholders, and ensure solutions are effective, compliant, and built for meaningful impact.

Roles & Responsibilities

• Lead medium-to-large digital, automation, data, analytics, and AI-enabled initiatives across multiple departments or functional areas from business need through implementation and adoption.
• Partner with Manufacturing, Business, Technology/IS, Engineering, Automation, Quality, Data, and vendor stakeholders to identify business needs, process improvements, and scalable technology solutions.
• Lead requirements elicitation and process analysis, translating business needs into system requirements, user stories, process flows, acceptance criteria, and measurable success criteria.
• Define and manage project scope, delivery plans, timelines, resources, budgets, risks, dependencies, milestones, and deliverables.
• Manage cross-functional teams through solution design, development, testing, implementation, release readiness, adoption, and post-implementation assessment.
• Support the computerized system/application lifecycle, including implementation, validation/qualification, change control, sustainment, enhancements, integrations, upgrades, periodic reviews, and retirement.
• Identify opportunities to simplify, standardize, and automate business processes, eliminate manual activities, improve data quality, and replace inefficient or legacy workflows.
• Partner with the business to identify, standardize, and operationalize data sources, metrics, KPIs, dashboards, and analytics solutions supporting operational excellence and data-driven decision-making.
• Drive delivery and adoption of digital platforms, workflow automation, dashboards, analytics, and AI-enabled capabilities that improve productivity, quality, decision-making, and user experience.
• Identify appropriate AI/ML and Generative AI use cases, support responsible AI adoption, and contribute to practical guidance and guardrails for AI platforms, tools, and applications.
• Ensure technology solutions comply with applicable Technology, cybersecurity, GxP, data integrity, quality, legal, policy, and operational requirements.
• Communicate project status, risks, decisions, technical approaches, dependencies, and business value to