Software Engineer, Staff: Applied AI, Science & Engineering

EngineersOfAI

New York (NY)

On-site

USD 180,000 - 240,000

Full time

5 days ago
Be an early applicant
Application generator

Stand out for this role — generate a tailored resume and cover letter in about a minute.

Get past ATS filters

Job summary

Anthropic is seeking an experienced software engineer to scale Claude-driven research and engineering efforts. You will work closely with scientists and engineers to convert open questions into concrete, testable tasks and build the systems that make Claude reliable and applicable across problems.

Responsibilities include integrating scientific computing tools, designing evaluations, and shipping pilots into partner workflows.

Qualifications

  • 8+ years of experience building software, with strong engineering fundamentals and comfort across the stack.
  • Have built real systems with large language models, including agents, tool use, or evaluations.

Responsibilities

  • Build Claude's agent harnesses and research loops from literature review to design iteration.
  • Connect scientific computing and simulation tools so Claude can drive them reliably and at scale.
  • Design evaluations to verify Claude's results and be honest about limits.
  • Work with partner scientists and engineers to turn problems into clear, verifiable tasks.
  • Prototype with partners, ship pilots, and prune non-essential work.
  • Refactor successful work into reusable tools and documented processes.
  • Explain Claude's results, limits, and tradeoffs to researchers and stakeholders.
  • Collaborate with research and product to improve models and roadmap.

Skills

Software engineering
LLM systems

Job description

About Anthropic

Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems.

About the role

At Anthropic, we're building AI systems that are safe, beneficial, and transformative. Our mission is to develop AI that benefits humanity, and we believe the most powerful capabilities emerge when we thoughtfully bridge the gap between research breakthroughs and real-world applications.

Claude is getting good at research. Given a well-posed problem, it can read the literature, write and run simulations, analyze results, and iterate on a design across physics, materials, chemistry, and engineering. But most of the hardest problems in science and engineering aren't well-posed. They live inside companies and labs with their own data, tools, constraints, and experts, and progress depends on turning all of that into work a model can actually do and check.

Our Applied AI, Science & Engineering team takes Claude to the scientists and engineers working on hard problems in energy, materials, hardware design, and other physical-world fields. We build the tools Claude needs to do real research and engineering work. Mostly that means software: the agent harnesses, integrations, evaluations, and working processes that turn a partner's problem into something Claude can make progress on and validate. We find real-world problems and test what we build through partner engagements, then feed our learnings back to our research and product teams. It's early, and the engineers who join now will shape how Claude gets applied to science and engineering.

This is an engineering role first. You'll spend real time with domain experts, become the person who knows how to get Claude working in their field, and prototype quickly alongside them. Most of your time, though, goes into building and hardening the systems that make that work repeatable, not into writing recommendations or configuring someone else's product. A science or engineering background is a big plus, but what matters most is that you can earn the trust of expert researchers, turn a fuzzy problem into something concrete and checkable, and ship.

Responsibilities
  • Build the agent harnesses and research loops that let Claude carry a problem from literature review through hypothesis generation, simulation, analysis, and design iteration
  • Connect scientific computing and simulation tools (finite element, CFD, electromagnetic, or molecular modeling codes, for example) so Claude can drive them reliably and at scale
  • Design and build evaluations that tell us whether Claude's work is actually right, and be honest about where it isn't
  • Sit with scientists and engineers at partner organizations to learn their problem, data, tools, and constraints, and turn open-ended questions into well-specified, verifiable tasks with clear success criteria
  • Prototype with partners, ship pilots into their workflows, and cut anything that doesn't move the problem forwardTurn what works in one engagement into shared tools, reusable components, and documented processes the next one can start from
  • Be the technical voice on how Claude performs on science and engineering work, explaining results, limits, and tradeoffs clearly to researchers, engineering leads, and non-technical stakeholders alike
  • Partner with our research and product teams to share where models fall short on science and engineering work, and help shape what comes next
You may be a good fit if you
  • Have 8+ years of experience building software, with strong engineering fundamentals and comfort across the stack, from data pipelines to tooling to quick interfaces
  • Have built real systems with large language models, including agents, tool use, or evaluations
Get your free, confidential resume review.

or drag and drop your file here.

Similar jobs

Similar jobs worth comparing

Staff Software Engineer (Applied AI, Science & Engineering)
Staff Software Engineer (Applied AI, Science & Engineering)

Anthropic • Seattle (WA)

On-site
USD 180,000 - 300,000
Comprehensive health, dental, and view
Fertility benefits
Parental leave (22 weeks)
+12
Applied AI Architect, International Policy
Applied AI Architect, International Policy

EngineersOfAI • San Francisco (CA)

Hybrid
USD 180,000 - 240,000
Staff+ Software Engineer, Claude Science San Francisco, CA
Staff+ Software Engineer, Claude Science San Francisco, CA

Anthropic Limited • San Francisco (CA), Northern (KY)

On-site
USD 405,000 - 485,000
Staff+ Software Engineer, Cybersecurity Products
Staff+ Software Engineer, Cybersecurity Products

Anthropic • San Francisco (CA)

On-site
USD 405,000 - 485,000
Staff+ Software Engineer, Enterprise AI Products
Staff+ Software Engineer, Enterprise AI Products

Anthropic • San Francisco (CA)

On-site
USD 405,000 - 485,000
Technical Enablement Lead, Claude Platform
Technical Enablement Lead, Claude Platform

WinsAbove • San Francisco (CA)

On-site
USD 270,000 - 310,000
Equity donation matching (optional)
Generous vacation
Parental leave
+2
Applied AI Engineer, Beneficial Deployments (Life Sciences)
Applied AI Engineer, Beneficial Deployments (Life Sciences)

Admin's Choice • New York (NY)

Hybrid
USD 280,000 - 320,000
Applied AI Systems Engineer, Science & Engineering
Applied AI Systems Engineer, Science & Engineering

EngineersOfAI • New York (NY)

On-site
USD 180,000 - 240,000
Technical Architect
Technical Architect

Precision Labs • San Francisco (CA), Northern (KY)

Hybrid
USD 250,000 - 365,000
Technical Architect
Technical Architect

WinsAbove • San Francisco (CA)

On-site
USD 250,000 - 365,000
Competitive compensation
Equity donation matching (optional)
Generous vacation
+3