Software Engineer II

Tempus AI; Chicago (IL); On-site; USD 85,000 - 130,000; Full time

Benefits offered by this job

Medical benefits

RSU/incentive compensation

Job summary

Tempus is seeking a Software Engineer to advance Genomics AI initiatives, leading analysis, design, and elected architecture decisions. You will mentor teammates, craft code across full-stack systems, and embed AI tooling to accelerate feature delivery in a fast-paced environment.

The role focuses on backend/frontend development with React/Node.js, REST/GraphQL APIs, and cloud pipelines in an agile setting.

Qualifications

• 3+ years of professional software development in an agile environment.
• Proficiency in TypeScript/JavaScript, Node.js and frontend frameworks like React.
• Experience with GenAI coding tools and agents to assist in writing code and tests.
• Strong background in relational databases and caching solutions (PostgreSQL/MySQL, Redis).
• RESTful/GraphQL API design and microservice architectures; cloud CI/CD pipelines.

Responsibilities

• Own end-to-end design and delivery of core features for Genomics AI initiatives.
• Integrate GenAI tools and autonomous coding agents into workflows to accelerate development.
• Write clean, scalable code and participate in architecture decisions for microservices.
• Coordinate with PMs and other engineers; mentor junior team members.

Skills

3+ years software development

TypeScript/JavaScript

Node.js

React

AI tooling adoption

Mentoring others

Tools

PostgreSQL

MySQL

Redis

Docker

Kubernetes

GCP/AWS

Job description

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

About Our Teams

At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, scientists, and product managers. You and your team set the goals, build the software, deploy the code, and contribute to a growing software platform that will make a lasting impact in the field of cancer research and treatment.

About The Role

We are seeking a highly motivated and capable Software Engineer to further our Genomics AI initiatives. This person should have experience and interest in leading analysis and design of technical problems, mentoring & coaching emerging talent during this transformative time in Tech. This position requires experience with programming (full stack), relational data systems and algorithms development. Top candidates will also have experience crafting code while leveraging AI tooling and embedding agentic workflows in their product.

Why We’re Looking for You

• You bring solid experience on software development teams, stepping beyond feature execution into leading technical analysis, design, and tradeoffs.
• You excel at solving complex problems through data-driven, iterative software development in distributed, event-based architectures.
• You possess a strong command of modern backend and frontend technologies and are excited to leverage AI-assisted development tools to move faster and build smarter.
• You thrive in fast-paced, agile environments—helping coordinate cross-team collaboration, troubleshooting technical roadblocks, and documenting architecture.
• You take pride in mentoring other engineers, elevating engineering standards, and continuously learning alongside a collaborative team.

Responsibilities

• Own end-to-end design, implementation, and delivery of core features in service of team and quarterly goals.
• Integrate Generative AI tools and autonomous coding agents (e.g., GitHub Copilot, Cursor, Claude Code) into your workflow to accelerate feature development, streamline test generation, and rapidly prototype solutions.
• Write clean, resilient code using enterprise design patterns that are flexible, performant, and adaptable to evolving business requirements.
• Contribute to microservice and database architecture decisions, keeping scalability, caching strategies, and distributed performance top of mind.
• Proactively identify technical dependencies, surface roadblocks early, and coordinate with product managers and other engineering teams.
• Support junior team members through constructive code reviews, pair programming, and actionable coaching.

Technical Requirements

• 3+ years of professional software development experience in an agile development environment.
• Strong proficiency in TypeScript/JavaScript, Node.js, and modern frontend frameworks like React.
• Hands-on experience using GenAI coding tools and agents (e.g., Copilot, Cursor, LLM APIs) to assist in writing code, refactoring, writing unit/integration tests, and accelerating feature delivery.
• Solid experience working with relational databases (PostgreSQL or MySQL) and query optimization, as well as caching solutions (Redis).
• Proven track record designing RESTful/GraphQL APIs and building within distributed or microservice architectures.
• Hands-on experience with cloud platforms (GCP or AWS) and CI/CD development pipelines.

Bonus Points

• Experience building features that incorporate GenAI/LLM APIs into user-facing applications.
• Experience with Elasticsearch/Opensearch
• Experience with containerization and orchestration (Docker, Kubernetes).
• Background in biotech, genomics, or precision medicine.

CHI: $85,000-$130,000

The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.