Software Engineer II

Tempus AI, Inc.; Chicago (IL); On-site; USD 85,000 - 130,000; Full time

Benefits offered by this job

Restricted stock units

Medical benefits

Job summary

Tempus AI, Inc. is seeking a Software Engineer to advance Genomics AI initiatives. You will lead technical analysis, design, and implementation of features across full stack, collaborating with scientists and product managers in a fast-paced, agile environment.

You will craft scalable backend services, integrate GenAI tools, and mentor teammates while delivering high-quality software that supports precision medicine and real-world evidence for clinicians.

Qualifications

• 3+ years of professional software development in an agile environment.
• Proficiency with TypeScript/JavaScript, Node.js, and React.
• Experience designing RESTful/GraphQL APIs and microservices.
• Hands-on with GenAI tools and coding agents to accelerate delivery.
• Experience with relational databases and cloud CI/CD pipelines.

Responsibilities

• Own end-to-end design, implementation, and delivery of core features.
• Integrate Generative AI tools and autonomous coding agents into workflows.
• Write clean, resilient code with enterprise design patterns.
• Contribute to microservice and database architecture decisions.
• Mentor junior engineers and coordinate with product and other teams.
• Support testing, documentation, and cross-team collaboration.

Skills

TypeScript/JavaScript

Node.js

React

GenAI tooling

Relational databases

REST/GraphQL APIs

Cloud platforms

CI/CD pipelines

Mentoring

Tools

PostgreSQL

MySQL

Docker

Kubernetes

GitHub Copilot

LLM APIs

Job description

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

About our Teams

At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, scientists, and product managers. You and your team set the goals, build the software, deploy the code, and contribute to a growing software platform that will make a lasting impact in the field of cancer research and treatment.

About the Role

We are seeking a highly motivated and capable Software Engineer to further our Genomics AI initiatives. This person should have experience and interest in leading analysis and design of technical problems, mentoring & coaching emerging talent during this transformative time in Tech. This position requires experience with programming (full stack), relational data systems and algorithms development. Top candidates will also have experience crafting code while leveraging AI tooling and embedding agentic workflows in their product.

Why We’re Looking for You

You bring solid experience on software development teams, stepping beyond feature execution into leading technical analysis, design, and tradeoffs. You excel at solving complex problems through data-driven, iterative software development in distributed, event-based architectures. You possess a strong command of modern backend and frontend technologies and are excited to leverage AI-assisted development tools to move faster and build smarter. You thrive in fast-paced, agile environments—helping coordinate cross-team collaboration, troubleshooting technical roadblocks, and documenting architecture. You take pride in mentoring other engineers, elevating engineering standards, and continuously learning alongside a collaborative team.

Responsibilities

• Own end-to-end design, implementation, and delivery of core features in service of team and quarterly goals.
• Integrate Generative AI tools and autonomous coding agents (e.g., GitHub Copilot, Cursor, Claude Code) into your workflow to accelerate feature development, streamline test generation, and rapidly prototype solutions.
• Write clean, resilient code using enterprise design patterns that are flexible, performant, and adaptable to evolving business requirements.
• Contribute to microservice and database architecture decisions, keeping scalability, caching strategies, and distributed performance top of mind.
• Proactively identify technical dependencies, surface roadblocks early, and coordinate with product managers and other engineering teams.
• Support junior team members through constructive code reviews, pair programming, and actionable coaching.

Technical Requirements

• 3+ years of professional software development experience in an agile development environment.
• Strong proficiency in TypeScript/JavaScript, Node.js, and modern frontend frameworks like React.
• Hands-on experience using GenAI coding tools and agents (e.g., Copilot, Cursor, LLM APIs) to assist in writing code, refactoring, writing unit/integration tests, and accelerating feature delivery.
• Solid experience working with relational databases (PostgreSQL or MySQL) and query optimization, as well as caching solutions (Redis).
• Proven track record designing RESTful/GraphQL APIs and building within distributed or microservice architectures.
• Hands-on experience with cloud platforms (GCP or AWS) and CI/CD development pipelines.

Bonus Points

• Experience building features that incorporate GenAI/LLM APIs into user-facing applications.
• Experience with Elasticsearch/Opensearch.
• Experience with containerization and orchestration (Docker, Kubernetes).
• Background in biotech, genomics, or precision medicine.

Salary

• CHI: $85,000-$130,000

The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience.

Benefits

Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

Equal Opportunity

We are an equal opportunity employer.

We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Company Background

Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics.

We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. We’re looking for people who can change the world. Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced.