Single-Cell Genomics: Computational Scientist II

Dawar Consulting; South San Francisco (CA); On-site; USD 73,873 - 105,214; Full time

Benefits offered by this job

Medical benefits

Dental benefits

Vision benefits

Paid sick leave

401K

Job summary

Dawar Consulting is seeking a Computational Scientist II for a long-term contract in South San Francisco, CA. The role focuses on single-cell genomics and therapeutic discovery, analyzing large datasets and building computational pipelines using Python. Qualifications include a Ph.D.

in a quantitative life science field, strong scRNA-seq experience, and expertise in Python and statistics. Collaboration across multidisciplinary teams is essential for delivering biological insights that advance

Qualifications

• Ph.D. in a quantitative life science or related field.
• Experience analyzing large-scale single-cell RNA sequencing (scRNA-seq) datasets.
• Strong Python programming for scientific computing and data analysis.
• Excellent analytical and collaborative skills.

Responsibilities

• Analyze and interpret large-scale single-cell sequencing datasets.
• Develop and optimize workflows for Perturb-seq, CROP-seq, Sci-Plex and other functional genomics studies.
• Apply statistical and computational methods to identify biological mechanisms, therapeutic targets, and treatment responses.
• Collaborate with biologists, chemists, computational scientists, and cross-functional research teams to translate complex data into actionable insights.
• Develop reproducible data analysis pipelines using Python.
• Perform quality control, data integration, visualization and statistical analysis of large-scale genomics datasets.
• Integrate multimodal datasets, including single-cell, genomic, and clinical data, to support research and therapeutic development.
• Present findings through scientific reports, presentations, and collaborations with internal research teams.
• Maintain well-documented, reproducible computational workflows and contribute to continuous process improvements.

Skills

Python

Statistics

scRNA-seq

Data analysis

NGS

Communication

Education

Ph.D. in Computational Biology / Bioinformatics / CS / Statistics / Mathematics

Tools

Nextflow

Snakemake

SLURM

Job description

Dawar Consulting is seeking a Computational Scientist II for a long-term contract in South San Francisco, CA. The role focuses on single-cell genomics and therapeutic discovery, analyzing large datasets and building computational pipelines using Python. Qualifications include a Ph.D.

in a quantitative life science field, strong scRNA-seq experience, and expertise in Python and statistics. Collaboration across multidisciplinary teams is essential for delivering biological insights that advance