Senior Virology Scientist – Vaccine Research

CSL Ltd. ADR; Waltham (MA); On-site; USD 145,000 - 180,000; Full time

Job summary

CSL Seqirus in Waltham, MA, seeks a Principal Scientist to lead vaccine virology and immunology research, translating complex data into actionable guidance for seasonal and pandemic influenza programs. This onsite role combines hands-on laboratory work with strategic leadership across cross-functional teams.

Onsite five days a week, you will design and optimize assays, drive preclinical studies, mentor scientists, and collaborate with external partners to advance programs from concept to

Qualifications

• PhD in Virology, Immunology, Microbiology, Molecular Biology or related field with 5+ years postdoc/pro experience.
• Strong expertise in classical and molecular virology; hands-on assay development and troubleshooting.
• Experience with infectious-virus culture and titration, neutralization assays, and molecular virology techniques.
• Experience designing and interpreting preclinical vaccine or infectious-disease studies; integrate findings.
• Strong experimental design, statistics, and data visualization (GraphPad Prism).
• Demonstrated scientific leadership, project coordination, and mentoring experience.
• Publications, patents, or assay/platform development demonstrating research impact.
• Excellent written and verbal communication; ability to collaborate across cross-functional teams.
• Experience with BSL-2 safety and commitment to biosafety and reproducible science.

Responsibilities

• Lead vaccine research programs as a virology SME, translating priorities into milestones and deliverables.
• Design, develop, optimize, and troubleshoot virology and immunology assays for vaccine research.
• Plan and interpret preclinical immunogenicity and protection studies using relevant animal models.
• Apply rigorous experimental design and quantitative analysis for reproducible data; communicate findings clearly.
• Oversee CROs and external collaborators, troubleshoot data, and ensure project objectives.
• Mentor scientists and research staff, contribute to planning and platform development.
• Support assay transfer, qualification, and cross-site comparability; explore new technologies.

Skills

Virology

Immunology

Molecular biology

Experimental design

Leadership

Data analysis

Education

PhD in Virology/Immunology/Microbiology/Molecular Biology

Tools

GraphPad Prism

Pseudovirus platform

BSL-2/BSL-3 experience

Job description

CSL Seqirus in Waltham, MA, seeks a Principal Scientist to lead vaccine virology and immunology research, translating complex data into actionable guidance for seasonal and pandemic influenza programs. This onsite role combines hands-on laboratory work with strategic leadership across cross-functional teams.

Onsite five days a week, you will design and optimize assays, drive preclinical studies, mentor scientists, and collaborate with external partners to advance programs from concept to