Senior Trial Operations Lead – Phase 3 (Hybrid/Remote)

Xenon Pharmaceuticals Inc.; Boston (MA); Hybrid; USD 154,000 - 195,000; Full time

Benefits offered by this job

Base salary

Stock options

Medical

Dental

Vision

Short- & long-term disability

Life insurance

Employee Assistance Program

Travel insurance

401(k) / retirement savings

Job summary

Xenon Pharmaceuticals Inc. in Needham/Boston, MA seeks a Senior Manager, Trial Operations to lead Phase 3 trial delivery from start-up to closeout. Partners with Clinical Development, CMC, Regulatory Affairs and external vendors to drive strategy, risk management and high-quality delivery.

The role emphasizes vendor management, site feasibility, budget/timeline oversight, and cross-functional leadership in a hybrid, on-site/remote environment based in Boston, MA. Travel 5–10% may be required.

Qualifications

• Bachelor's degree in a scientific field or healthcare designation.
• Minimum 5–8 years of trial operations/clinical project management experience.
• Strong vendor management and CRO oversight experience.

Responsibilities

• Provide clinical trial management leadership for multiple Phase 3 trials across therapeutic areas.
• Collaborate with cross-functional teams to ensure integrated plans and documentation.
• Develop, review and manage study plans, timelines, and budgets; lead vendor selections.

Skills

Clinical trial management

Cross-functional leadership

Vendor management

Budget & timelines

Regulatory knowledge

Education

Bachelor's degree in a scientific discipline

Job description

Xenon Pharmaceuticals Inc. in Needham/Boston, MA seeks a Senior Manager, Trial Operations to lead Phase 3 trial delivery from start-up to closeout. Partners with Clinical Development, CMC, Regulatory Affairs and external vendors to drive strategy, risk management and high-quality delivery.

The role emphasizes vendor management, site feasibility, budget/timeline oversight, and cross-functional leadership in a hybrid, on-site/remote environment based in Boston, MA. Travel 5–10% may be required.