Senior Translational Strategy & Operations Lead

AstraZeneca; Boston (MA); On-site; USD 142,000 - 214,000; Full time

Benefits offered by this job

401(k) plan

Vacation and holidays

Paid leaves

Health benefits

Job summary

AstraZeneca is a global biopharmaceutical company focused on discovery, development and commercialization of medicines. This role sits in Hematology R&D, Translational Medicine, leading biomarker studies and coordinating data across teams to drive decision-making.

The successful candidate will translate complex questions into coordinated workplans, leverage multi-omic data, and collaborate with internal and external partners to accelerate translational science and early clinical development.

Qualifications

• Master’s degree with 6+ years relevant experience or Ph.D. with 2+ years relevant experience.
• Excellent interpersonal and communication skills.
• Outstanding ability to work independently and with a team, including problem solving, brainstorming, integrating data and helping other team members.
• Experience in highly matrixed structures in the pharmaceutical industry, diagnostics industry, or similar industries.
• Excellent organizational and documentation skills.
• Excellent data presentation skills.
• Familiarity with genomic and molecular data and the systems used to manage and present it.
• Ability to critically evaluate scientific data, methods, and validation evidence from external partners.
• Experience in highly matrixed structures in the pharmaceutical industry, diagnostics industry, or similar industries.

Responsibilities

• Serves as a scientific integrator across Translational Medicine Leads, data scientists, translational research scientists, project teams, and internal and external stakeholders, connecting scientific objectives, data-generation plans, analytical approaches, and operational execution.
• Applies deep scientific knowledge of multi-omic and phenotypic markers to support translational efforts and biomarker strategies such as tissue profiling, liquid biopsy, and MRD on an indication basis.
• Drives evaluation of external partners, conducting scientific and technical due diligence to inform partnership decisions, including MRD strategy.
• Leads internal and external meetings to drive translational deliverables, identify needs and risks, and develop risk mitigation strategies.
• Presents and maintains relevant dashboards and associated data, leads coordination of science, and reports progress and projections across data science and the translational research portfolio.
• Coordinates compliance for samples and associated data moving into and out of internal and external laboratories, partnering with compliance, legal, quality, data science, and biosafety.
• Successfully navigates objectives within matrixed teams of non-direct reports and influences without direct authority.
• Other responsibilities as needed.

Skills

Interpersonal communication

Independent & team work

Data integration

Matrixed organizations

Organizational skills

Documentation skills

Data presentation

Genomic data familiarity

Critical data evaluation

External partner collaboration

Education

Master’s degree + 6+ years

Ph.D. + 2+ years

Job description

AstraZeneca is a global biopharmaceutical company focused on discovery, development and commercialization of medicines. This role sits in Hematology R&D, Translational Medicine, leading biomarker studies and coordinating data across teams to drive decision-making.

The successful candidate will translate complex questions into coordinated workplans, leverage multi-omic data, and collaborate with internal and external partners to accelerate translational science and early clinical development.