Senior Translational Biomarker Scientist

Arrowhead Pharmaceuticals

Madison (WI)

On-site

USD 120,000 - 180,000

Full time

14 days+

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Job summary

Arrowhead Pharmaceuticals in Madison, WI seeks a Senior Scientist to lead translational biomarker strategies for drug development candidates. The role focuses on designing robust biomarker assays, validating GCLP processes, and advancing early projects through translational and clinical development.

The candidate will bring extensive experience in translational biomarker technologies and strong communication skills to thrive in a fast-paced, matrixed environment, with possible mentoring

Qualifications

  • PhD in biology or chemistry related sciences with 5+ years of industrial translational biomarker experience.
  • Experience in assay development, GCLP validation, and soluble biomarker assays for clinical studies.
  • Strong skills in immunochemical techniques, protein biochemistry, LC-MS and molecular biology.
  • Excellent organizational skills in a fast-paced, matrixed environment.

Responsibilities

  • Design, develop, and execute fit-for-purpose clinical biomarker assays for PD and response.
  • Identify and evaluate new technologies to support translational biomarker strategies.
  • Collaborate with CROs to transition and monitor assays to external vendors.
  • Drive advancement of early-stage projects into translational and clinical development.
  • May lead Associate Scientists as a manager or mentor.
  • Authors and oversees documentation through GCLP-regulated testing stages.

Skills

Biomarker assay development
Clinical biomarker strategy
Communication skills
Problem solving
Organizational skills

Education

PhD in Biology or Chemistry related sciences

Tools

GCLP validation
LC-MS
Immunochemical techniques
Protein biochemistry
Molecular biology techniques
qPCR
ELISA

Job description

Arrowhead Pharmaceuticals in Madison, WI seeks a Senior Scientist to lead translational biomarker strategies for drug development candidates. The role focuses on designing robust biomarker assays, validating GCLP processes, and advancing early projects through translational and clinical development.

The candidate will bring extensive experience in translational biomarker technologies and strong communication skills to thrive in a fast-paced, matrixed environment, with possible mentoring

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