Associate Scientist II, Molecular Biology

Arrowhead Pharmaceuticals; Madison (WI); On-site; USD 65,000 - 78,000; Full time

Benefits offered by this job

Competitive salaries

Excellent benefit package

Job summary

A biopharmaceutical company in Madison, WI is seeking an Associate Scientist II to join their Translational Biomarkers Team. The role involves conducting assays to support drug discovery, requiring a Bachelor's in Biology and expertise in cellular techniques. Ideal candidates have 3+ years of relevant experience and strong problem-solving skills. Competitive salary between $65,000—$78,000, alongside a comprehensive benefits package.

Qualifications

• 3+ years of experience in cell biology, molecular biology, immunology, pharmacology, or a related field, OR a Master’s Degree with 1+ years of experience.
• Demonstrated ability to innovate, think creatively, and solve problems with resilience.
• Excellent oral and written communication skills.

Responsibilities

• Conduct and execute in vitro, ex vivo, and/or in vivo studies to support drug discovery.
• Propose innovative methods and strategies to optimize cell-based functional assays.
• Engage in gene expression and functional analysis using a variety of methodologies.
• Assist in identifying and validating new targets for transformative therapies.

Skills

Cell culture

ELISA

Cell-based assays

Immunofluorescence

Western blotting

Microscopy

RNA/DNA isolation

qPCR

Education

Bachelor of Science in Biology or related field

Job description

Overview

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis and includes targets in liver, lung, and other areas. Our corporate headquarters are in Pasadena, CA, with research and development in Madison, WI & San Diego, CA, and a manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators collaborating to bring new therapies to patients in need.

Position

Associate Scientist II, Translational Biomarkers — We are seeking an Associate Scientist II to join the Translational Biomarkers Team in Madison, WI. This role supports the development and execution of assays for clinical trial samples, demonstrating attention to detail, strong record-keeping, and cross-functional collaboration while leveraging technical expertise.

Responsibilities

• Conduct and execute in vitro, ex vivo, and/or in vivo studies to support drug discovery and development with a level of independence that fosters creativity.
• Propose innovative methods and strategies to optimize cell-based functional assays and contribute to research efforts.
• Perform cell-based functional assays that lead to discoveries.
• Engage in gene expression and functional analysis using a variety of methodologies.
• Assist the team in identifying and validating new targets with potential for transformative therapies.
• Occasionally present research findings to project teams and governance bodies and prepare internal technical reports reflecting contributions.
• Stay informed by reviewing relevant scientific literature and applying insights to projects to address challenges.
• Maintain high productivity and quality in the laboratory, ensuring excellence in every experiment.
• Maintain meticulous records and conduct activities in accordance with GCLP best practices, ensuring high standards of work.

Requirements

• Bachelor of Science in Biology or a related field
• 3+ years of experience in cell biology, molecular biology, immunology, pharmacology, or a related field, OR a Master’s Degree with 1+ years of experience
• Proficiency in standard cellular and molecular biology techniques such as cell culture, ELISA, cell-based assays, immunofluorescence, Western blotting, microscopy, RNA/DNA isolation, and qPCR
• Demonstrated ability to innovate, think creatively, and solve problems with resilience
• Excellent oral and written communication skills
• A self-motivated team player who thrives in a fast-paced, multi-disciplinary, matrixed environment

Preferred

• Experience in pulmonary, cardiovascular, CNS, or metabolic disease
• A foundational understanding of commonly used RNA and protein assays

Compensation and Location

Location: Madison, WI

Wisconsin pay range: $65,000—$78,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

All applicants must have authorization to work in the US. California Applicant Privacy Policy may apply where required.

Note: This description reflects the responsibilities and requirements for the role at the time of posting and is subject to change.