Senior System Engineer

Twist Bioscience Corporation; Wilsonville (OR); On-site; USD 120,000 - 180,000; Full time

Job summary

Twist Bioscience Corporation seeks a Senior Systems Engineer to join onsite in Wilsonville, OR. Lead development, validation, and integration of automated laboratory instrumentation and bioprocess technologies, interfacing hardware, software, and biology to drive quality.

You will design automated workflows, write integration scripts, and connect robotic systems with enterprise LIMS to ensure operational excellence under ISO 13485.

Qualifications

• Ph.D. or MS with 3 years, BS with 5 years in engineering fields.
• Experience in developing automated instrumentation for bioprocesses.
• Experience with DoE for testing and troubleshooting of processes.
• Scripting experience in C# or Python for lab automation systems.
• Interfaces between robotic instrumentation and LIMS (MES/Maestro, Twist build).
• Strong data analysis and communication skills.

Responsibilities

• Develop, validate, and release new processes to improve quality and cost-effectiveness.
• Develop and test protocols, scripts, and systems to automate bioprocesses.
• Operate and maintain lab automation instruments and cross-integration systems.
• Collaborate with cross-disciplinary teams to troubleshoot equipment issues.
• Prepare documentation, knowledge transfer, and training materials.
• Follow ISO 13485 requirements.

Skills

C# scripting

Python

Data analysis

Hardware assembly

Lab automation

Regulatory awareness

Education

PhD in Biomedical Engineering

MS in Biomedical Engineering

BS in Engineering

Tools

LIMS interfaces

Maestro integration

Twist build interfaces

Control software

Job description

Sr. Systems Engineer (Onsite in Wilsonville, OR)

Summary

We are seeking a Senior Systems Engineer to join our team in Portland, OR (PDX). In this role, you will lead the development, validation, and integration of cutting-edge automated laboratory instrumentation and bioprocess technologies. Working at the intersection of hardware, software, and biology, you will design automated workflows, write custom integration scripts, and connect robotic systems with enterprise LIMS infrastructure to drive operational excellence and product quality under ISO 13485 standards.

What You’ll Do

• Develop, validate, and release new processes and technologies to achieve cost-effectiveness and improved product quality
• Develop and test protocols, scripts, and systems to automate certain bioprocesses
• Operation and maintenance of a range of scientific instruments and tools with a focus on laboratory automation systems and cross-integration systems
• Collaborate with multi-disciplinary teams in troubleshooting and resolving issues concerning equipment and systems
• Prepare and participate in documentation, knowledge transfer, and training activities
• Follow regulatory and ISO 13485 requirements

What You’ll Bring

• Ph.D. or MS with 3 years, BS with 5 years of related experience in Biomedical Engineering, Chemical Engineering, Mechanical/Electrical Engineering, or related field
• Experience in developing automated instrumentation for bioprocesses
• Experience with DoE for testing and troubleshooting of certain processes
• Experience in designing and writing scripts (C#, Python, etc) using control software or dynamic scheduling software native to laboratory automation systems and cross-integration systems
• Experience with sample tracking software and developed interfaces between robotic instrumentation and LIMS systems (MES/Maestro, Twist build)
• Excellent scientific computation and data analysis capabilities
• Hands-on skills to assemble and maintain hardware
• Experience with biological instrumentation for liquid transfer, PCR, cell-based cloning, DNA extraction, and purification is desirable
• Working collaboratively with other functional groups
• Excellent communication and writing skills, and ability to work in a fast-paced team environment

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.